2025
Heintz MM , Buerger AN, Haws LC, Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049 . PMID: 40216583.
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Publication: Manuscripts
/ Topics: mode of action , transcriptomics
Wikoff D . An introduction to evidence integration. Workshop Session, Abstract 1333, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , NAMs
Wikoff D, Fitch S , Vincent M, Southall MD, Atillasoy E, Weinstein RD, Ejaz SD, Rhoden JD, Choksi N . Biological plausibility assessment of acetaminophen and occurrence of developmental neurological outcomes in humans. Abstract 4768, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025. (Honored as one of the Risk Assessment Specialty Section’s Top 10 Abstracts ).
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , pharmacology
Thompson CM, Heintz MM , Cullen JM, Haws LC. Evaluation of the chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate (HFPO-DA) in mice. Abstract 4700, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: ammonium , carcinogens
Proctor D, Thompson C . Why oral cavity tumors should not be the basis of the hexavalent chromium oral cancer slope factor-weight of evidence review. Abstract 3136, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025. (Honored as one of the Risk Assessment Specialty Section’s Top 10 Abstracts ).
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Publication: Abstracts and Presentations
/ Topics: Cancer , chromium
Mihalchik A . Strategies to evaluate over-the-counter drug degradants. Abstract 1252, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , pharmacology
Lea IA , Holt J, Bunnage E, Long M, Chew R, Bell S, Edwards S, Sayre R, Vliet SM, Lynn SG, Kristan MJ. Integrated computational approaches in systematic evidence mapping: Bridging human expertise and machine learning for advanced toxicological assessments. Abstract 3409, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: risk assessment , Systematic Review
Klaren W . Targeted state of the science scoping review for incorporating stress within experimental models of chemical toxicity. Abstract 1260, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: scoping review
Klaren W . Incorporating stress as a variable into toxicological testing: Advancing our understanding of cumulative impacts. Abstract 1259, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Heintz MM, Buerger AN, Haws LC, East AW, Cullen JM, Thompson CM . Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mice. Abstract 3972, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025
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