2024
East A, Klaren W , Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology , Toxicology
Covington TR, Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR) , Systematic Review
Reátegui-Zirena EG, Lange SS, Jenkins A, Heintz MM , Franke K, Perry CS, Thompson C, et al. Acute health-based screening level derivation for cyanotoxins (microcystin, cylindrospermopsin and anatoxins). Abstract 7.05P-Th-197, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology , Toxicology
Perry CS , Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 . PMID: 39251127.
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Publication: Manuscripts
/ Topics: Air Quality , Manganese , modeling , PBPK
Jackson JW, Frederick C Streich Jr, Pal A, Coricor G, Boston C, …, Wood M , et al. 2024. An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis. Sci Signal 17(844): DOI: 10.1126/scisignal.adn6052.
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Publication: Manuscripts
/ Topics: Toxicology
Thompson CM , Dewhurst N, Moundous D, Borghoff SJ , Haws LC, Vasquez MZ. 2024. Assessment of the genotoxicity of tert-butyl alcohol in an in vivo thyroid comet assay. Environ Mol Mutagen 65(3–4):129–136; doi: 10.1002/em.22601 . PMID: 38717101.
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Publication: Manuscripts
/ Topics: Toxicology
Panko J, Mittal L , Franke K, Maberti S, Zollers S, Millison K, et al. 2024. Industry-wide review of potential worker exposure to 1,3-butadiene during chemical manufacturing and processing as a reactant. J Occup Environ Hyg 21(1):13-23; doi: 10.1080/15459624.2023.2264329 . PMID: 37788445.
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