2024
Yoshino T, Hooda N , Younan D, Muro K, Shitara K, Heinemann V,… Suh M , Reichert H , Mezzi K, Fryzek J , et al. 2024. A meta-analysis of efficacy and safety data from head-to-head first-line trials of epidermal growth factor receptor inhibitors versus bevacizumab in adult patients with RAS wild-type metastatic colorectal cancer by sidedness. Eur J Cancer 202:113975, doi: 10.1016/j.ejca.2024.113975 .
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Topics: Cancer , Epidemiology , Systematic Review
Nelms MD, Antonijevic T, Ring C, Harris DL, Bever RJ, Lynn SG, … Borghoff S , et al. 2024. Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models. Front Toxicol 6:https://doi.org/10.3389/ftox.2024.1346767 .
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Topics: Toxicology
Mittal L , Perry C , Blanchette AD, Proctor DM . 2024. Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese. Risk Analysis, open access .
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Topics: Cancer , Toxicology
Heintz MM , Klaren WD , East AW , Haws LC , McGreal SR, Campbell RR, Thompson CM . 2024. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in mouse, rat, and pooled human hepatocytes. Toxicol Sci kfae044. doi: 10.1093/toxsci/kfae044 . Online ahead of print. PMID: 38574381
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Topics: PFAS , Toxicology
Heintz MM , Klaren WD , East AW , Haws LC , McGreal SR, Campbell RR, Thompson CM . 2024. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mouse hepatocytes. Toxicol Sci kfae045. doi: 10.1093/toxsci/kfae045 . Online ahead of print. PMID: 38574385.
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Topics: PFAS , Toxicology
Bever RJ, Edwards SW, Antonijevic T, Nelms MD, Ring C, Harris D, Lynn SG, Williams D, Chappell G, Boyles R, Borghoff S , Markey KJ. 2024. Optimizing androgen receptor prioritization using high-throughput assay-based activity models. Front Toxicol 6:1347364; doi: 10.3389/ftox.2024.1347364 .
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Topics: Toxicology
Racz L , Gauthier A , Bare J , Heintz M , Feifarek D , Kennedy S , Panko J . 2024. Assessment of perfluorocarboxylic acids in fluorinated high-density polyethylene containers and estimation of potential non-cancer risks associated with anticipated use scenarios. Regul Toxicol Pharmacol 147:105560; doi: 10.1016/j.yrtph.2024.105560 .
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Topics: Toxicology
Fitch S, Blanchette A, Haws LC, Franke K , Ring C, DeVito M,… Wikoff DS . 2024. Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 147:105571; doi: 10.1016/j.yrtph.2024.105571.
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Topics: Systematic Review , Toxicology
DeVito M, Bokkers B, van Duursen MBM, van Ede K, Feeley M, Antunes Fernandes Gaspar E, Haws L ,… Wikoff DD , et al. 2024. The 2022 World Health Organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Regul Toxicol Pharmacol 146:105525; doi: 10.1016/j.yrtph.2023.105525
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Topics: Epidemiology
2023
Ring C, Blanchette A, Klaren WD , Fitch S , Haws L , Wheeler MW, DeVito MJ, Walker N, Wikoff D . 2023. A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 143(11):105464; doi: 10.1016/j.yrtph.2023.105464.
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