2025
Wikoff DS, Vincent MJ, Heintz MM , Pastula ST, Reichert H, Klaren WD , Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Topics: PFAS , risk assessment , Systematic Review , Toxicology
Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 .
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Topics: phthalates
Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 .
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Topics: Cancer , carcinogens , MTBE , risk assessment
Rogers JM , Buerger AN, Heintz MM, Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 .
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Topics: phthalates
Lea IA , Buerger AN, Feifarek D, Mihalchik A, Heintz MM , Haws LC, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 .
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Topics: phthalates
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
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Topics: Ecology , risk assessment , Toxicology
Lipworth L, Panko JM, Allen BC, Mumma MT, Jiang X, Vincent MJ, Bare JL, Antonijevic T, Vivanco SN, Marano DE, Suh M , Cohen S, Mittal L , Proctor DM. 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
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Topics: Cancer , chromium , Exposure Assessment , Hexavalent Chromium , Occupational
2024
Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D . 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723 .
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Topics: Food science , risk assessment , Toxicology
Perry CS , Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 .
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Topics: Manganese , modeling , PBPK
Jackson JW, Frederick C Streich Jr, Pal A, Coricor G, Boston C, …, Wood M , et al. 2024. An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis. Sci Signal 17(844): DOI: 10.1126/scisignal.adn6052.
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