Publication Topic

Mihalchik AL, Roberts A, LaCombe J, Lloyd M, Doepker C, Eapen A. 2026. Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica. Toxicol Rep 17(Dec):102297; doi: 10.1016/j.toxrep.2026.102297. PMID: 42388455.

East A, Klaren W, Wikoff D, Patlewicz G. Identifying potential co-exposures with food additives using data mining and machine learning approaches across EPA’s Consumer Product Database (CPDat). Abstract M-36, Poster Session, International Society of Exposure Science (ISES) 2026 Annual Meeting, Vancouver, BC, Canada, October 5, 2026.

Schaefer HR, Frankenfeld CL, Wikoff D. 2026. Low- and no-calorie sweeteners lack shared target organs or modes of action required for cumulative risk assessment. Food Chem Toxicol 116424; doi: 10.1016/j.fct.2026.116424. PMID: 42829191. Online ahead of print October 3.

Summan M, Doepker CL, Brorby GP. 2026. Safety evaluation of an aqueous root and leaf extract of Ashwagandha (Withania somnifera). Phytother Res 40(8):5030-5047; doi: 10.1002/ptr.70314. PMID: 41987003.

Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Session 8, 11^th International Congress of the Asian Society of Toxicology (ASIATOX-XI), Kuala Lumpur, Malaysia, August 2026.

Fitch S, Lozy F, Mitchell C, Patlewicz G, Wood A. Use of new approach methodologies in the safety assessment of dietary supplements—Parts one and two. Webinar series, Council for Responsible Nutrition (CRN), Washington, DC, May 2026.

Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

Mahony C, Bartlett A, Fitzpatrick S, Galli C, Hunt P, Inselman A, Jimenez J,…, Rogers J, et al. 2026. A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals. 64(1):639-557; doi: 10.1080/13880209.2026.2659421. PMID: 42048162.

Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Abstract 3653, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, East A, Wheeler M, Vincent M, Wikoff DS, Covington T. Probabilistic estimation of daily total nitrosamine exposures generated from drinking water and dietary nitrate and nitrate sources. Abstract 3982, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.