Publication Topic

Kennedy SB, Heintz MM, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Defining the domain of applicability: A case study to increase confidence in toxicogenomic tools for ecological risk assessment. Poster 1.03.P-Tu032, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 19, 2026.

Thompson CM, Heintz MM, Rogers SI, Vincent MJ, Haws LC. 2026. Integration of mechanistic and repeat dose toxicity data in the derivation of an oral reference dose for HFPO-DA. Toxicol Sci 209(5):kfag045; doi: 10.1093/toxsci/kfag045. PMID: 41968070.

Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

Lea IA, Buerger AN, Vincent MJ,…, Choksi NY, Schaefer H, Britt J, Fitch S, Haws L, Borghoff SJ. 2026. Evaluating the potential carcinogenic hazard of diisononyl phthalate in humans via systematic integration of human, animal cancer studies, and mechanistic data. Curr Res Toxicol 10(Apr 30):100295; doi: 10.1016/j.crtox.2026.100295.

Buerger AN, Thompson CM, Heintz MM, Maberti S, Palermo CM, Haws LC. 2026. Application of quantitative and qualitative uncertainty assessment risk management decision-making: A case study with diisononyl phthalate. Food Chem Toxicol 116110; doi: 10.1016/j.fct.2026116110. Online ahead of print April 25. PMID: 42035978.

Vincent M, Wheeler M, Schaefer H, Rhoden J, Fitch S, Wikoff D. Quantitative bias assessment to facilitate assessment of (un)certainty in observational data evaluating acetaminophen use and liver cancer. Abstract 4279, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Patlewicz G, Mihalchik A, Thompson CM, East A, Borghoff S. Investigating the feasibility of deriving a new environmentally relevant Thresholds of Toxicological Concern (TTCs) from estimated human equivalent benchmark dose (eBMD_HED) values. Abstract 4013, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Wheeler M, Wikoff D, Vincent M. Annealed Bayesian bias assessment in epidemiological studies. Session M2-H, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Hoffman S, Wikoff D, Brown L, Wheeler M. Advancing quantitative uncertainty assessment in next generation risk assessment. Session T2-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.