Publication Topic

Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci; doi: 10.1093/toxsci/kfae152. Online ahead of print 10 Jan 2025. PMID: 39792025.

Lea IA, Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Wikoff D, Fitch S. 2024. Evidence‐based methods in toxicology: Systematic review and systematic evidence mapping. Chapter 32 in: Paustenbach DJ (ed), Human and Ecological Risk Assessment: Theory and Practice, Third Edition, pp. 1133–1148. Wiley, ISBN: 978-1-119-74296-8.

Yoshino T, Hooda N, Younan D, Muro K, Shitara K, Heinemann V,… Suh M, Reichert H, et al. 2024. A meta-analysis of efficacy and safety data from head-to-head first-line trials of epidermal growth factor receptor inhibitors versus bevacizumab in adult patients with RAS wild-type metastatic colorectal cancer by sidedness. Eur J Cancer 202:113975, doi: 10.1016/j.ejca.2024.113975.

Fitch S, Blanchette A, Haws LC, Franke K, Ring C, DeVito M,… Wikoff DS. 2024. Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 147:105571; doi: 10.1016/j.yrtph.2024.105571.

Rivera BN, Svetlik A, Klaren WD, Wikoff DS, Henderson RG. Scoping review of the immunomodulatory effects of cannabidiol: Effects within T cells. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

Borghoff SJ, Cohen SS, Jiang X, Lea IA, Klaren WD, Chappell GA, Britt JK, Rivera BN, Choksi NY, Wikoff DS. 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172:113549, online ahead of print.

Henderson RG, Franke KS, Payne LE, Franzen A. 2022. Cannabidiol safety data: A systematic mapping study. Cannabis Cannabinoid Res (epub ahead of print), doi: 10.1089/can.2022.0100, PMID: 36251454.

Doepker C, Movva N, Cohen SS, Wikoff DS. 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol (in press, journal pre-proof available online).