Publication Topic

Rivera BN, Lea IA, Fitch S, Choksi N, Franzen A, Bus J, Rushton E, Borghoff SJ. 2025. Systematic evaluation of the evidence base on ethyl tert-butyl ether and tert-butyl alcohol for carcinogenic potential in humans: Lack of concern based on animal cancer studies and mechanistic data. Curr Res Tox 10(Nov 10):100270; doi: 10.1016/j.crtox.2025.100270. PMID: 41446581.

Suh M, Movva N, Izikson R, La Via W, Pastula S, Machado MAA, Shin T, Rizzo C. The burden of respiratory syncytial virus among young children in the United States is not well-documented across settings: A systematic literature review. Abstract P2192, IDWeek, Atlanta GA, October 2025.

Fitch S, Rogers J, Marty S, Norman J, Schneider S, Rushton E, Wikoff D, Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci 207(2):289-305; doi: 10.1093/toxsci/kfaf108. PMID: 40794567.

Clouser MC, Suh M, Movva N, Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966. PMID: 40729867.

Lea IA, Holt J, Bunnage E, Long M, Chew R, Bell S, Edwards S, Sayre R, Vliet SM, Lynn SG, Kristan MJ. Integrated computational approaches in systematic evidence mapping: Bridging human expertise and machine learning for advanced toxicological assessments. Abstract 3409, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152. PMID: 39792025.

Wikoff D, Fitch S. 2024. Systematic reviews and evidence-based methods in toxicology. In: Wexler P (ed), Encyclopedia of Toxicology. Elsevier, pp. 875–882.

Lea IA, Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Wikoff D, Fitch S. 2024. Evidence‐based methods in toxicology: Systematic review and systematic evidence mapping. Chapter 32 in: Paustenbach DJ (ed), Human and Ecological Risk Assessment: Theory and Practice, Third Edition, pp. 1133–1148. Wiley, ISBN: 978-1-119-74296-8.