2025
Heintz MM , Buerger AN, Haws LC, Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049 . PMID: 40216583.
View Abstract
Publication: Manuscripts
Heintz MM, Buerger AN, Haws LC, East AW, Cullen JM, Thompson CM . Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mice. Abstract 3972, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025
View Abstract
Publication: Abstracts and Presentations
2022
Heintz MM , Chappell GA, Thompson CM , Haws LC. 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
View Abstract
Publication: Manuscripts
Chappell GA, Wolf JC, Thompson CM . 2021. Crypt and villus transcriptomic responses in mouse small intestine following oral exposure to hexavalent chromium. Toxicol Sci 186(1):43-57; doi: 10.1093/toxsci/kfab152 . PMID: 34935971.
View Abstract
Publication: Manuscripts
2021
Chappell GA, Heintz MM , Haws LC. 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41; doi: 10.1016/j.crtox.2021.01.003 .
View Abstract
Publication: Manuscripts
2019
Chappell GA, Thompson CM , Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.
Publication: Abstracts and Presentations
Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C . Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
View Abstract