Tice RR, Bassan A, Amberg A, Anger LT, Beal MA, Bellion P, Benigni R, Birmingham J, Brigo A, Bringezu F, Ceriani L, Crooks I, Cross K, Elespuru R, Faulkner DM, Fortin MC, Fowler P, Frericks M, Greets HHJ, Jahnke GD, Jones DR, Krulak NL, Piparo EL, Lopez-Belmonte J, Luniwal A, Luu A, Madia F, Manganelli S, Manickam B, Mestres J, Mihalchik-Burhans AL , Neilson L, Pandiri A, Pavan M, Rider CV, Rooney JP, Trejo-Martin A, Wantanabe-Sailor KH, White AT, Wooley D, Myatt GJ. 2021. In silico approaches in carcinogenicity hazard assessment: Current status and future needs. Comp Toxicol 20:100191 (Special issue: The in silico toxicology protocols initiative).
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Publication: Manuscripts
/ Topics: Toxicology
2021
Franke K , Payne L , Franzen A , Wikoff D , Henderson R . 2021. Cannabidiol literature scoping review protocol. Center for Open Science, OSFHOME (May 20).
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Publication: Manuscripts
/ Topics: Systematic Review
Wikoff D , Edwards S, Angrish M, Baumgartner, Bever R, Borghoff S , Chappell G , Chew R, Fitch S , Hench G, Hamernik K, Henderson D, Kirk A, Lea I , Mandel M, Payne L , Shapiro S, Urban J , Williams D, Markey K. Application of systematic methods to characterize thyroid adverse outcome pathways (AOPs). Presented at 10th annual meeting of American Society for Cellular and Computational Toxicology (virtual), October 2021.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review , Toxicology
Black MB, Andersen ME, Pendse SN, Borghoff SJ , Streicker M, McMullen PD. 2021. RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days. Data in Brief 38:107420. doi: 10.1016/j.dib.2021.107420. PMID: 34660856; PMCID: PMC8502903.
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Publication: Manuscripts
/ Topics: Toxicology
Palermo CM, Foreman JE, Wikoff DS , Lea I . 2021. Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol 22:2:254–271. doi: 10.1016/j.crtox.2021.07.002. PMID: 34401750; PMCID: PMC8350458.
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Publication: Manuscripts
/ Topics: Toxicology
Gentry R, Rodricks J, Clewell H, Greene T, Chappell G , Lea I , Borghoff S , Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A. 2021. RE: Response to the Office of Environmental Health Hazard Assessment on comments related to Gentry et al. (2021). Food Chem Toxicol 152:112202. doi: 10.1016/j.fct.2021.112202. Epub 2021 Apr 17. PMID: 33872725.
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Publication: Manuscripts
/ Topics: Toxicology
Gentry R, Greene T, Chappell G , Lea I , Borghoff S , Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A, Rodricks J, Clewell H. 2021. Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors. Food Chem Toxicol 151:112097. doi: 10.1016/j.fct.2021.112097. Epub 2021 Mar 4. PMID: 33677041.
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Publication: Manuscripts
/ Topics: Toxicology
Lea IA , Chappell GA , Wikoff DS . 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869:503389. doi: 10.1016/j.mrgentox.2021.503389. PMID: 34454695.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Wikoff D, Fitch S, Borghoff S. Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff): 61st Annual Meeting (virtual) of the Society for Birth Defects Research & Prevention, June 2021.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Wikoff D. The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Fitch SE , Payne LE , van de Ligt JLG , Doepker C , Handu D, Cohen SM, Anyangwe N, Wikoff D . 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Public Health 21(1):956, doi: 10.1186/s12889-021-10934-2.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Borghoff SJ , Fitch SE , Black MVB, McMullen PD, Andersen ME, Chappell GA . 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124:104977; DOI: 10.1016/j.yrtph.2021.104977.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Whaley P, Blaauboer BJ, Brozek J, Cohen Hubal EA, Hair K, Kacew S, Knudsen TB, Kwiatkowski CF, Mellor DT, Olshan AF, Page MJ, Rooney AA, Radke E, Shamseer L, Tsaioun K, Tugwell P, Wikoff D , Woodruff TJ. 2021. Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do. ALTEX [Internet] .
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Publication: Manuscripts
/ Topics: Systematic Review
Proctor DM , Bhat V, Suh M , Reichert H , Jiang X , Thompson CM . 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124:104969, doi.org/10.1016/j.yrtph.2021.104969.
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Publication: Manuscripts
/ Topics: Hexavalent Chromium , Toxicology
de Vries RBM, Angrish M, Browne P, Brozek J, Rooney AA, Wikoff DS , Whaley P, Edwards SW, Morgan RL, Druwe IL, Hoffmann S, Hartung T, Thayer K, Avey MT, Beverly BEJ, Falavigna M, Gibbons C, Goyak K, Kraft A, Nampo F, Qaseem A, Sears M, Singh JA, Willett C, Yost EY, Schünemann H, Tsaioun K. 2021. Applying evidence-based methods to the development and use of adverse outcome pathways. ALTEX — Alternatives to Animal Experimentation, 38(2):336–347, doi: 10.14573/altex.2101211.
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Publication: Manuscripts
/ Topics: Systematic Review
Saili KS, Antonijevic T , Zurlinden TJ, Shah I, Deisenroth C, Knudsen TB. 2020. Molecular characterization of a toxicological tipping point during human stem cell differentiation. Reprod Toxicol 91:1–13 (selected as journal’s best paper of 2020 ).
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Publication: Manuscripts
/ Topics: Toxicology
Dirven H, Vist GE, Bandhakavi S, Mehta J, Fitch SE , Pound P, Ram R, Kincaid B, Leenaars CHC, Chen M, Wright RA, Tsaioun K. 2021. Performance of preclinical models in predicting drug-induced liver injury in humans: A systematic review. Nature, Scientific Reports; open access .
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Chappell GA, Heintz MM, Borghoff SJ, Doepker CL, Wikoff DS . 2021. Lack of potential carcinogenicity for steviol glycosides — Systematic evaluation and integration of mechanistic data into the totality of evidence. Food Chem Toxicol 150:112045.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Felter SP, Zhang X, Thompson C . 2021. Butylated hydroxyanisole: Carcinogenic food additive to be avoided or harmless antioxidant important to protect food supply? Regul Toxicol Pharmacol 121:104887.
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Publication: Manuscripts
/ Topics: Toxicology
Thompson CM , Gentry R, Fitch S , Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952, DOI: 10.1080/10408444.2020.1854679.
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Publication: Manuscripts
/ Topics: Toxicology
Gentry R, Thompson CM , Franzen A , Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918, DOI: 10.1080/10408444.2020.1854678.
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Publication: Manuscripts
/ Topics: Toxicology
Wikoff DS , Urban JD , Ring C, Britt J , Fitch S , Haws LC . 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182, https://doi.org/10.1093/toxsci/kfaa171.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Chappell GA , Heintz MM , Haws LC . 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41.
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Publication: Manuscripts
/ Topics: Toxicology
Chappell GA , Wikoff DS , Thompson CM . 2021. Assessment of mechanistic data for hexavalent chromium-induced rodent intestinal cancer using the key characteristics of carcinogens. Toxicol Sci 180(1):38–50.
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Publication: Manuscripts
/ Topics: Toxicology
2020
Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118:104788.
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Publication: Manuscripts
/ Topics: Toxicology
Whaley P, Aiassa E, Beausoleil C, Beronius A, Bilotta, G, Boobis A, de Vries R, Hanberg A, Hoffman S, Hunt N, Kwiatkowski CF, Lam J, Lipworth S, Martin O, Randall, N, Rhomberg L, Rooney AA, Holger J, Schünemann HJ, Wikoff D , Wolffe T, Halsall C. 2020. Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER). Environ Int 143:105926.
Publication: Manuscripts
/ Topics: Systematic Review
Chappell GA , Wikoff DS , Doepker CL , Borghoff SJ . 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141:111375 [open access ].
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Publication: Manuscripts
/ Topics: Systematic Review
Chappell GA , Britt JK , Borghoff, SJ . 2020. Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes. Food Chem Toxicol 140:111310 [open access] .
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Publication: Manuscripts
/ Topics: Systematic Review
Haws L (session co-chair). Introduction to “Use of New Approach Methods in Risk Characterization of PFAS: Challenges and Opportunities.” 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/894 ).
Publication: Abstracts and Presentations
/ Topics: Toxicology
Ring C . Application of high-throughput exposure modeling in risk-based prioritization for PFAS. Presentation at 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/900 ).
Publication: Abstracts and Presentations
/ Topics: Toxicology
Antonijevic T , Shah I. Predicting subchronic and chronic animal toxicity from in vitro high content imaging data using PBTK and machine learning. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Henderson RG , Franzen A , Franke K , Payne L , Schmitt D , Wikoff D . Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Ring C , Fitch S , Haws L , Harris M , Wikoff D . Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Suh M , Verwiel A , Proctor D . Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Thompson CM , Ring C , Pham L, Chappell GA , Haws LC . Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Wikoff D , Franzen A , Chappell G , Harris M , Thompson C . Systematic characterization of hexavalent chromium and potential female reproductive outcomes: Application of US EPA critical appraisal tools and stepwise inclusion of mechanistic data. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium , Toxicology
Pham LL, Borghoff SJ , Thompson CM . 2020. Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values. Regul Toxicol Pharmacol 113:104651 [open access ].
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Publication: Manuscripts
/ Topics: Toxicology
Bell S, Mansouri K, Phillips J, Chang X, Abedini J, Karmaus AL, Lea I , Rai R, Allen DG, Casey W, Kleinstreuer NC. NCEATM computational tools and resources supporting alternative test method development and evaluation. Presented at the 59th Annual Meeting of Society of Toxicology, Anaheim CA, March 2020. Abstract #2976-P607.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Lea IA , Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK. 2007. Genetic pathways and mutation profiles of human cancers: Site- and exposure-specific patterns. Carcinogenesis 28:1851–1858.
Publication: Manuscripts
/ Topics: Toxicology
Wikoff DS , Bennett DC, Brorby GP , Franke KS. 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam Part A ; DOI: 10.1080/19440049.2020.1727963.
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Publication: Manuscripts
/ Topics: Toxicology
2019
Chappell GA , Borghoff SJ , Pham L, Doepker CL , Wikoff DS . 2019. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110898.
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/ Topics: Systematic Review
Yoon M, Ring C, Van Landingham CB, Suh M , Song G, Antonijevic T , Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695
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Publication: Manuscripts
/ Topics: Toxicology
Fitch S, Goyak K, Green Maia, Grimm F, Wikoff D . 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework , August.
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Publication: Protocol Registrations
/ Topics: Systematic Review
Wikoff D , Haws L Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol , doi: 10.1002/jat.3814, open access.
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Publication: Manuscripts
/ Topics: Toxicology
Rager JE, Suh M , Chappell G , Thompson CM , Proctor DM . 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305:40–50.
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Publication: Manuscripts
/ Topics: Chrome VI
Sheridan E, Moose J, Liu Y, Martini C, Lea I , Fostel J. NTP high-level summary data collections in the Chemical Effects in Biological Systems (CEBS) database. Presented at the 15th International Congress of Toxicology, Honolulu, HI, July 2019. Poster PS01-0606.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Bhawana B, Lea I , Liu Y, Martini C, Fostel J. Access to National Toxicology Program histopathology lesion collection in Chemical Effects in Biological Systems (CEBS) database. Presented at the 38th Annual Symposium of Society for Toxicologic Pathology, Raleigh, NC, June 2019. Poster P040.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Lea I , Liu Y, Sheridan E, Motti D, Martini C, Fostel J, Auerbach S. Hallmark gene set annotation for NTP toxicogenomic studies. Presented at the 58th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2019. Abstract #1743-P119.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I , Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Presented at the 58th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2019. Abstract #1749-P125.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Suh M , Wikoff D , Lipworth L, Goodman M, Fitch S , Mittal L , Ring C, Proctor D . 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol [ePub ahead of print]: doi: 10.1080/10408444.2019.1578730.
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Publication: Manuscripts
/ Topics: Hexavalent Chromium , Systematic Review
Wikoff DS , Rager JE, Chappell GA , Fitch S , Haws L , Borghoff SJ . 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335.
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Publication: Manuscripts
2018
Kimzey AL , Piche M-S, Wood M , Weir AB, Lansita J . 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427 .
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Publication: Book Chapters
/ Topics: Toxicology
Tsaioun K, Dirven H, Beck Færden K, Wikoff D , Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S . 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353 .
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Publication: Manuscripts , Protocol Registrations
/ Topics: Toxicology
Borghoff SJ, Fitch S , Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99:168–181.
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Publication: Manuscripts
/ Topics: PFAS , Toxicology
Moffat I, Martinova N, Seidel C, Thompson CM. 2018. Hexavalent chromium in drinking water. Journal AWWA 110:5.
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Publication: Manuscripts
/ Topics: Chrome VI
Wikoff D , Goodrum P, Haws L , Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
Urban JD , Harvey S , Haws LC , Wikoff D . Assessment of study quality (risk of bias) in understanding the relationship between congenital heart defects (CHDs) and exposures to trichloroethylene (TCE). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
Wikoff D . Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Borghoff S , Wikoff D , Urban JD , Rager JE . A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Proctor DM. Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA). Thresholds in Toxicology and Risk Assessment Fall Symposium. Oakland, CA,November 14, 2018.
Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium
Thompson CM, Wolf JC, Suh M, Proctor DM , Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018
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Publication: Abstracts and Presentations
/ Topics: Chrome VI
Thompson CM, Suh M, Proctor DM , Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.
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Publication: Abstracts and Presentations
/ Topics: Chrome VI
Proctor, DM . Updating the regulatory risk assessment for hexavalent chromium in California: Implications for regulatory standards. Association of Environmental Health Sciences San Diego, CA, March 20, 2018.
Publication: Abstracts and Presentations
/ Topics: Chrome VI
Thompson CT , Suh M , Chappell G , Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.
Publication: Manuscripts
/ Topics: PFAS , Toxicology
Suh M , Proctor DM , Chappell G , Rager JE , Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403:50-67, doi: 10.1016/j.tox.2018.04.006.
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Publication: Manuscripts
/ Topics: Toxicology
Proctor DM , Suh M , Chappell G , Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol , 96:30-40, doi: 10.1016/j.yrtph.2018.04.016.
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Publication: Manuscripts
/ Topics: Toxicology
Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I , Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Presented at the 57th Annual Meeting of Society of Toxicology, San Antonio, TX, March 2018. Abstract 2525-P887.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Lea IA , Borghoff S, Travlos GS. 2018. Electrolytes, blood gases and acid-base balance. In: Kurtz DM, Travlos GS (eds): The Clinical Chemistry of Laboratory Animals (3rd edition). CRC Press, Boca Raton, FL (https://doi.org/10.1201/9781315155807 ).
Publication: Book Chapters
/ Topics: Toxicology
Brorby GP . 2018. The ongoing controversy surrounding the effects of short-term exposure to trichloroethene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, March 19–22, San Diego, CA.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE, Proctor DM , Rager JE , Haws LC , Harris MA . 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545.
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Publication: Manuscripts
/ Topics: Hexavalent Chromium
Verougstraete V, Henderson R , Mackie C, Newson T, Oller A. 2018. Human health (toxicity) assessment of complex inorganic materials. In: Verougstraete V (ed), Risk Management of Complex Inorganic Materials. Elsevier Inc. ISBN 978-0-12-811063-8.
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Publication: Book Chapters
/ Topics: Metals
Wikoff D, Urban JD, Harvey S, Haws LC . 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol , DOI: 0.1177/1091581818754330.
View Abstract