2016
Worth A, Patlewicz G . 2016. Integrated approaches to testing and assessment. Adv Exp Med Biol 856:317-342; doi: 10.1007/978-3-319-33826-2_13 . PMID: 27671729.
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Publication: Book Chapters
/ Topics: Adverse outcome pathways (AOPs) , safety assessment
Patlewicz G , Worth AP, Ball N. 2016. Validation of computational methods. Adv Exp Med Biol 856:165-187; doi: 10.1007/978-3-319-33826-2_6 . PMID: 27671722.
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Publication: Book Chapters
/ Topics: computational toxicology , read-across
Wikoff D , Borghoff S , Rager J, Harvey S , Haws L. 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429 Available from: http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016046429
Publication: Protocol Registrations
/ Topics: Systematic Review
Wikoff D , Borghoff S , Rager J, Harvey S , Haws L . 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429 .
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Publication: Protocol Registrations
/ Topics: carcinogens , Epidemiology , Systematic Review
Richard A, Judson R, Houck K, Grulke C, Volarath P, Thillainadarajah I, Yang C,…, Patlewicz G , et al. 2016. The ToxCast chemical landscape: Paving the road to 21st century toxicology. Chem Res Toxicol 29(8):1225-1251; doi: 10.1021/acs.chemrestox.6b00135 . PMID: 27367298.
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Publication: Manuscripts
/ Topics: computational toxicology
Shah I, Liu J, Judson RS, Thomas R, Patlewicz G . 2016. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. Reg Toxicol Pharmacol 79(Aug):12-24; doi: 10.1016/j.yrtph.2016.05.008 . PMID: 27174420.
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Publication: Manuscripts
/ Topics: read-across
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80:60-70; doi: 10.1016/j.yrtph.2016.05.031 .
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Publication: Manuscripts
/ Topics: Air Quality , Systematic Review , titanium dioxide
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM . 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 .
View Abstract
Publication: Manuscripts
/ Topics: Air Quality , Systematic Review , titanium dioxide
Klaren WD , Vine D, Vogt S, Robertson LW. Evaluation of the spatial distribution of hepatic metals following PCB126 exposure with x-ray fluorescence microscopy. Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.
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Publication: Abstracts and Presentations
/ Topics: Metals , PCBs
Gadupudi GS, Klaren WD , Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology, Central States Regional Meeting, Iowa City, IA, 2016. Also presented at NIEHS Obesity Grantee Meeting and 25 Years of Endocrine Disruption Workshop, NIH, Bethesda, MD, 2016.