Publication Topic

Patlewicz G, Mihalchik A, Thompson CM, East A, Borghoff S. Investigating the feasibility of deriving a new environmentally relevant Thresholds of Toxicological Concern (TTCs) from estimated human equivalent benchmark dose (eBMD_HED) values. Abstract 4013, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Lea I, Rivera B, Rogers S, Borghoff SJ. Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence. Abstract 5206, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Lea IA, Rivera B, Rogers S, Borghoff SJ. 2026. Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence. Curr Res Toxicol 10:100284; doi: 10.1016/j.crtox.2026.100284. PMID: 41755915.

Covington TR, Borghoff SJ, Brorby GP, Doepker CL, Wikoff DS, Franzen AC. Using IVIVE to address systemic exposure challenges in genotoxicity testing of complex mixtures. Poster Session PO-41, American Society for Cellular and Computational Toxicology (ASCCT) 14th Annual Meeting, Gaithersburg, MD, October 2025.

Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490. PMID: 40320068.

Hagan B, Groff L, Patlewicz G, Shah. 2025. Toward metabolic similarity in read-across: A case study using graph convolutional networks to predict genotoxicity outcomes. Chem Res Toxicol 38(6):1122-1133; doi: 10.1021/acs.chemrestox.5c00120. PMID: 40432291.

Thompson CM, Dewhurst N, Moundous D, Borghoff SJ, Haws LC, Vasquez MZ. 2024. Assessment of the genotoxicity of tert-butyl alcohol in an in vivo thyroid comet assay. Environ Mol Mutagen 65(3–4):129–136; doi: 10.1002/em.22601. PMID: 38717101.

Thompson CM, Brorby G, Keig-Shevlin Z, Smith R, Franzen A, Ulrich K, Blanchette AD, Doepker C. 2023. Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures. Environ Mol Mutagen 64(8–9):420–431; doi: 10.1002/em.22576. PMID: 37916278.

Thompson CM, Kirman C, Harris MA. 2023. Derivation of oral cancer slope factors for hexavalent chromium informed by pharmacokinetic models and in vivo genotoxicity data. Regul Toxicol Pharmacol 145(Dec):105521; doi: 10.1016/j.yrtph.2023.105521. PMID: 37863416.

Henderson RG, Welsh BT, Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Genotoxicity evaluation of cannabidiol. Regul Toxicol Pharmacol 142(August):105425; doi: 10.1016/j.yrtph.2023.105425. PMID: 37271419.