2025
Brorby G, Franzen A, Thompson C, Wikoff D , Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490 . PMID: 40320068.
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Publication: Manuscripts
Hagan B, Groff L, Patlewicz G , Shah. 2025. Toward metabolic similarity in read-across: A case study using graph convolutional networks to predict genotoxicity outcomes. Chem Res Toxicol 38(6):1122-1133; doi: 10.1021/acs.chemrestox.5c00120 . PMID: 40432291.
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Publication: Manuscripts
2023
Thompson CM , Brorby G , Keig-Shevlin Z, Smith R, Franzen A , Ulrich K, Blanchette AD, Doepker C. 2023. Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures. Environ Mol Mutagen 64(8–9):420–431; doi: 10.1002/em.22576 . PMID: 37916278.
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Publication: Manuscripts
Thompson CM , Kirman C, Harris MA. 2023. Derivation of oral cancer slope factors for hexavalent chromium informed by pharmacokinetic models and in vivo genotoxicity data. Regul Toxicol Pharmacol 145(Dec):105521; doi: 10.1016/j.yrtph.2023.105521 . PMID: 37863416.
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Publication: Manuscripts
Henderson RG , Welsh BT, Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Genotoxicity evaluation of cannabidiol. Regul Toxicol Pharmacol 142(August):105425; doi: 10.1016/j.yrtph.2023.105425 . PMID: 37271419.
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Publication: Manuscripts
2021
Thompson CM , Aardema MJ, Heintz MM , MacGregor JT, Young RR. 2021. A review of mammalian in vivo genotoxicity of hexavalent chromium: Implications for oral carcinogenicity risk assessment. Crit Rev Toxicol 51(10)820-849; doi: 10.1080/10408444.2021.2000934 . PMID: 35060824.
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Publication: Manuscripts
Lea IA , Chappell GA, Wikoff DS . 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869(Aug-Sept):503389; doi: 10.1016/j.mrgentox.2021.503389 . PMID: 34454695.
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Publication: Manuscripts
Patlewicz G , Dean J, Gibbons C, Judson R, Keshava N, Vegosen L, Martin T, Pradeep P, et al. 2021. Integrating publicly available information to screen potential candidates for chemical prioritization under the Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity. Comput Toxicol 20(Nov):100185; doi: 10.1016/j.comtox.2021.100185 . PMID: 35128218.
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Publication: Manuscripts
Pradeep P, Judson RS, DeMarini DM, Keshava N, Martin TM, Dean J, Gibbons CF,…, Patlewicz G . 2021. An evaluation of existing QSAR models and structural alerts and development of new ensemble models for genotoxicity using a newly compiled experimental dataset. Comput Toxicol 18(May):100167; doi.org/10.1016/j.comtox.2021.100167 . PMID: 34504984.
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Publication: Manuscripts
2018
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol, 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 .
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