Publications

Lizarraga LE, Patlewicz G, Dean JL II, Zhao QJ, Kaiser JP. 2021. Provisional peer-reviewed toxicity values for 3,4-toluenediamine (CASRN 496-72-0). Cincinnati (OH): U.S. Environmental Protection Agency; 2021 Aug. PMID: 36191119.

Tate T, Wambaugh J, Patlewicz G, Shah I. 2021. Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study. Comput Toxicol 19(Aug):100171; doi: 10.1016/j.comtox.2021.100171. PMID: 37309449.

Doepker CD, Heintz MM, van de Ligt JLG, Wikoff DS. 2021. Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits. Trans Anim Sci 5(4):txab203; doi: 10.1093/tas/txab203. PMID: 34909600.

Wikoff D, Fitch S, Borghoff S. Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff): 61^st Annual Meeting of the Society for Birth Defects Research & Prevention, Virtual, June 2021.

Wikoff D. The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.

Haddadin Z, Rankin DA, Lipworth L, Suh M, McHenry R, Blozinski A, Salib George S, Fernandez KN, et al. 2021. Respiratory virus surveillance in infants across different clinical settings. J Pediat 234(July):p164-p171; doi: 10.1016/j.jpeds.2021.03.036. PMID: 33774057.

Fitch SE, Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Pub Health 21(1):956; doi: 10.1186/s12889-021-10934-2. PMID: 34016063.

Borghoff SJ, Fitch SE, Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124(Aug):104977; doi: 10.1016/j.yrtph.2021.104977. PMID: 34174380.

Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E… Wikoff D, et al. 2021. Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential. Regul Toxicol Pharmacol 120(March):104859; doi: 10.1016/j.yrtph.2020.104859. PMID: 33388367.

Kimzey A, Mease K, Mounho-Zamora B, Wood M. 2021. 13. Biosimilar products—A review of past and current regulatory approval standards for preclinical safety studies. In: Translational Medicine: Optimising Preclinical Safety Evaluation of Biopharmaceuticals. CRC Press: Boca Raton, FL.