2025
Klaren W . Targeted state of the science scoping review for incorporating stress within experimental models of chemical toxicity. Abstract 1260, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: scoping review , Toxicology
Klaren W . Incorporating stress as a variable into toxicological testing: Advancing our understanding of cumulative impacts. Abstract 1259, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , Toxicology
Heintz MM, Buerger AN, Haws LC, East AW , Cullen JM, Thompson CM . Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mice. Abstract 3972, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025
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Publication: Abstracts and Presentations
/ Topics: PFAS , Toxicology
Fitch S, Wikoff D , Foreman J, Buerger A, Haws L, Palmero C. Assessment of relative potency factors for six phthalates. Abstract 4235, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: phthalates , Toxicology
Cook B, Nelms M, Harris D, Bever RJ, Lynn SG, Williams D, Borghoff S , Edwards SW, Markey K. Identifying structural overlap between EDSP universe of chemicals and ToxCast/Tox21 using chemical clustering and uniform manifold approximation and projection. Abstract 4034, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Buerger AN, Vincent MJ, Fitch S , Rushton EK, Borghoff SJ . Evaluation of potential obesogenicity through a mode of action approach: A case study with MTBE. Abstract 3928, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: MTBE
Borghoff SJ, Rivera BN, Fitch S, Buerger A, Choksi N, Franzen A , Bus J, Rushton EK, Lea I . Systematic evaluation of the evidence base on methyl tert-butyl ether for carcinogenic potential in humans; Low concern based on animal cancer studies and mechanistic data. Abstract 4702, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: carcinogens , MTBE
Wikoff DS, Vincent MJ, Heintz MM , Pastula ST, Reichert H, Klaren WD , Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Publication: Manuscripts
/ Topics: PFAS , risk assessment , Systematic Review , Toxicology
Lea IA , Feifarek D, Mihalchik A, Heintz M , Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
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Publication: Manuscripts
/ Topics: phthalates
Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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