Publications

Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

Lea IA, Rivera B, Rogers S, Borghoff SJ. 2026. Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence. Curr Res Toxicol 10:100284; doi: 10.1016/j.crtox.2026.100284. PMID: 41755915.

Patlewicz G, Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2026. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B 29(1):1-69; doi: 10.1080/10937404.2025.2521615. PMID: 40619890.

Wambaugh JF, Sipes NS, Padilla Mercado G, Arnot JA, Bertato L, Brown TN, Chirico N,…, Patlewicz G, et al. 2026. Collaborative evaluation of in silico predictions for high throughput toxicokinetics. Toxicol In Vitro 110(Jan):106150; doi: 10.1016/j.tiv.2025.106150. PMID: 40983213.

Thompson CM, Heintz MM, Cullen JM, Haws LC. 2026. Evaluation of chronic toxicity and carcinogenicity of HFPO-DA in mice. Regul Toxicol Pharmacol 165(Feb):106014; doi: 10.1016/j.yrtph.2025.106014. PMID: 41391658.

Choksi N, McMillan D, Schmitt D, Doepker C, Henderson RG. 2026. Demonstration of safety for rice bran wax and sunflower wax based on bridging to other naturally derived waxes used in food. Regul Toxicol Pharmacol 165(Feb):105990; doi: 10.1016/j.yrtph.2025.105990. PMID: 41248699.

Wheeler M, Wikoff D, Vincent M. Annealed Bayesian bias assessment in epidemiological studies. Session M2-H, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Hoffman S, Wikoff D, Brown L, Wheeler M. Advancing quantitative uncertainty assessment in next generation risk assessment. Session T2-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Heintz MM, Kennedy SB, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Toxicogenomics in ecological risk assessment: Current landscape, research gaps and recommendations to increase confidence across sectors. Abstract 1.02.T-01, SETAC North America 46^th Annual Meeting, Portland, OR, November 2025.

Rivera BN, Lea IA, Fitch S, Choksi N, Franzen A, Bus J, Rushton E, Borghoff SJ. 2025. Systematic evaluation of the evidence base on ethyl tert-butyl ether and tert-butyl alcohol for carcinogenic potential in humans: Lack of concern based on animal cancer studies and mechanistic data. Curr Res Tox 10(Nov 10):100270; doi: 10.1016/j.crtox.2025.100270. PMID: 41446581.