2025
Allen BC, Vincent MJ , Lipworth L, Panko JM, Suh M, Jiang X , Mumma MT, Proctor DM . 2025. Lung cancer risk assessment associated with exposure to hexavalent chromium: Results of pooled analysis of three cohorts. J Occup Environ Hyg 22(10):821-835; doi: 10.1080/15459624.2025.2502491 . PMID: 40435461.
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Publication: Manuscripts
/ Topics: Cancer , chromium , Exposure Assessment , risk assessment
Covington TR, Borghoff SJ, Brorby GP, Doepker CL, Wikoff DS, Franzen AC . Using IVIVE to address systemic exposure challenges in genotoxicity testing of complex mixtures. Poster Session PO-41, American Society for Cellular and Computational Toxicology (ASCCT) 14th Annual Meeting, Gaithersburg, MD, October 2025.
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Publication: Abstracts and Presentations
/ Topics: genotoxicity
Borghoff SJ, Heintz MM , Rivera BN, Haws L, Thompson C . 2025. Evaluation of an anti-thyroid mode of action for thyroid follicular cell adenomas in female mice exposed to tertiary butyl alcohol. Regul Toxicol Pharmacol 163(Dec):105936; doi: 10.1016/j.yrtph.2025.105936 . PMID: 40914479.
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Publication: Manuscripts
/ Topics: mode of action , water
Fitch S , Rogers J , Marty S, Norman J, Schneider S, Rushton E, Wikoff D , Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci 207(2):289-305; doi: 10.1093/toxsci/kfaf108 . PMID: 40794567.
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Publication: Manuscripts
/ Topics: microplastics , Systematic Review
Wambaugh JF, Sipes NS, Padilla Mercado G, Arnot JA, Bertato L, Brown TN, Chirico N,…, Patlewicz G , et al. 2026. Collaborative evaluation of in silico predictions for high throughput toxicokinetics. Toxicol In Vitro 110(Jan):106150; doi: 10.1016/j.tiv.2025.106150 . ePub September 20, 2025. PMID: 40983213.
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Publication: Manuscripts
/ Topics: toxicokinetics
Klaren WD , Rivera BN, Sheppard AM, Franke K, Wikoff DS . 2025. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Curr Res Toxicol 9(Sep):100256; doi: 10.1016/j.crtox.2025.100256 . PMID: 41030520.
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Publication: Manuscripts
/ Topics: food additives , food safety , Food science
Patlewicz G , Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366 .
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Publication: Manuscripts
/ Topics: NAMs
Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G , et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083 . PMID: 39937625.
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Publication: Manuscripts
/ Topics: ecotoxicology , NAMs
Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G . 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152 . PMID: 40680271.
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Publication: Manuscripts
/ Topics: modeling
Proctor D, Jiang X, Reichert H, Thompson C . 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci kfaf112; doi: 10.1093/toxsci/kfaf112 . Online ahead of print August 8, 2025. PMID: 40795394.
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