Wikoff D , Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment
Wikoff D . Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: regulatory toxicology , risk assessment , Systematic Review
Borghoff S , Wikoff D , Urban JD , Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: Cancer , food safety , Food science , mode of action
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86 . PMID: 30070899.
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Publication: Manuscripts
/ Topics: Toxicology
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
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Publication: Manuscripts
/ Topics: modeling
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337; doi: 10.1093/toxsci/kfy109 .
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Publication: Manuscripts
/ Topics: Systematic Review
Patlewicz G , Cronin MTD, Helman G, Lambert JC, Lizarraga LE, Shah I. 2018. Navigating through the minefield of read-across frameworks: A commentary perspective. Comput Toxicol 6(May):39-54; doi: 10.1016/j.comtox.2018.04.002 .
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Publication: Manuscripts
/ Topics: computational toxicology , NAMs
Thompson CM , Wolf JC, Suh M , Proctor DM, Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: carcinogens , chromium
Thompson CM , Suh M , Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: chromium , mode of action
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189; doi: 10.1016/j.yrtph.2018.05.006 .
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