2017
Judson RS, Martin M, Patlewicz G , Wood CE. 2017. Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study. Regul Toxicol Pharmacol 86(June):74-92; doi: 10.1016/j.yrtph.2017.02.015 . PMID: 28242142.
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Publication: Manuscripts
/ Topics: modeling
Mease K, Kimzey A , Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol 4(June):1–15; doi: 10.1016/j.cotox.2017.03.005 . PMID: 29658009.
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Publication: Manuscripts
/ Topics: biomarkers
Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5):621-640; doi: 10.1002/jat.3412 . PMID: 27885692.
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Publication: Manuscripts
/ Topics: modeling , pharmacokinetics
Greene T, Rogers S, Franzen A , Gentry R. 2017. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol 47(2):98–120; doi: 10.1080/10408444.2016.1236071 . PMID: 27834107.
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , Exposure Assessment , food additives , mode of action
Fitzpatrick J, Patlewicz G . 2017. Application of IATA – A case study in evaluating the global and local performance of a Bayesian network model for skin sensitization. SAR QSAR Environ Res 28(4):297-310; doi: 10.1080/1062936X.2017.1311941 . PMID: 28423913.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs) , Bayesian modeling
Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I , Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Poster P035. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017.
Publication: Abstracts and Presentations
/ Topics: computational toxicology
Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S . 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.
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Publication: Abstracts and Presentations
/ Topics: carcinogens , Systematic Review
Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at 56th Society of Toxicology Annual Meeting. March 15, Baltimore, MD, March 2017.
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Publication: Abstracts and Presentations
/ Topics: chromium
Borghoff SJ , Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Thompson C , Kirman C, Suh M , Proctor D, Haws L, Harris M, Hays S. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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