2019
Wikoff DS , Rager JE, Chappell GA, Fitch S , Haws L, Borghoff SJ . 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335.
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Publication: Manuscripts
/ Topics: carcinogens
2018
Kimzey AL , Piche M-S, Wood M , Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427 .
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Publication: Book Chapters
/ Topics: Toxicology
Tsaioun K, Dirven H, Beck Færden K, Wikoff D , Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S . 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353 .
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Publication: Manuscripts , Protocol Registrations
/ Topics: Toxicology
Borghoff SJ, Fitch S , Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001 .
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Publication: Manuscripts
/ Topics: PFAS , Toxicology
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
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Publication: Manuscripts
/ Topics: chromium , Cr(VI) MOA Study , Hexavalent Chromium
Grimm FA, Klaren WD , Li X, House JS, Chiu W, Lehmler HJ, Robertson LW, Rusyn I. Cardiotoxicity screening of polychlorinated biphenyls and their major metabolites. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
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Publication: Abstracts and Presentations
/ Topics: PCBs , Toxicology
Klaren WD , Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Urban JD , Harvey S , Haws LC, Wikoff D . Assessment of study quality (risk of bias) in understanding the relationship between congenital heart defects (CHDs) and exposures to trichloroethylene (TCE). Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
Wikoff D . Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Wikoff D , Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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