2023
Franzen AC, Thompson CM, Brorby GP , Wikoff DS , Ilkbahar Z, Doepker C. Risk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: food additives , food safety , Food science , risk assessment
Fitch S, Rogers J, Marty S, Ellis-Hutchings R, Becker R, Wikoff D . Development of a study quality tool for use in a systematic review of literature reporting microplastic exposure and reproductive and developmental toxicity. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: microplastics , Systematic Review
Thompson CM , Proctor DM , Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 . PMID: 36916184.
Publication: Manuscripts
/ Topics: carcinogens , dose-response , regulatory toxicology
Patlewicz G , Shah I. 2023. Towards systematic read-across using Generalized Read-Across (GenRA). Comput Toxicol 25(Feb):100258; doi: 10.1016/j.comtox.2022.100258 . PMID: 37693774.
View Abstract
Publication: Manuscripts
/ Topics: NAMs
Houck K, Paul Friedman K, Feshuk M, Patlewicz G , Smeltz M, Clifton S, Wetmore BA, Velichko S, et al. 2023. Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells. ALTEX 40(2):248–270; doi: 10.14573/altex.220304 . PMID: 36129398.
View Abstract
Publication: Manuscripts
/ Topics: chemical safety assessment , PFAS
Adams M, Hilde H, Chang D, Richard A, Williams AJ, Shah I, Patlewicz G . 2023. Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalized Read-Across (GenRA) approach. Comput Toxicol 25(Feb):100256; doi: 10.1016/j.comtox.2022.100256 . PMID: 36733411.
View Abstract
Publication: Manuscripts
/ Topics: NAMs
Boyce M, Favela KA, Bonzo JA, Chao A, Lizarraga L, Moody LR, Owens EO, Patlewicz G , et al. 2023. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis. Front Toxicol 5(Jan 18):1051483; doi: 10.3389/ftox.2023.1051483 . PMID: 36742129.
View Abstract
Publication: Manuscripts
/ Topics: spectrometry
Lizarraga L, Suter GW, Lambert JC, Patlewicz G , Zhao JQ, Dean JL, Kaiser P. 2023. Advancing the science of a read-across framework for evaluation of data poor chemicals incorporating systematic and new approach methods. Regul Toxicol Pharm 137(Jan):105293; doi: 10.1016/j.yrtph.2022.105293 . PMID: 36414101.
View Abstract
Publication: Manuscripts
/ Topics: NAMs
Borghoff SJ , Cohen SS, Jiang X , Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN , Choksi NY, Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
View Abstract