2024
Tate T, Patlewicz G , Shah I. 2024. A comparison of machine learning approaches for predicting hepatotoxicity potential using chemical structure and targeted transcriptomic data. Comput Toxicol 29(March):100301; doi: 10.1016/j.comtox.2024.100301 . PMID: 38993502.
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Topics: transcriptomics
Bever RJ, Edwards SW, Antonijevic T, Nelms MD, Ring C, Harris D, Lynn SG, Williams D, Chappell G, Boyles R, Borghoff S , Markey KJ. 2024. Optimizing androgen receptor prioritization using high-throughput assay-based activity models. Front Toxicol 6(March 11):1347364; doi: 10.3389/ftox.2024.1347364 . PMID: 38529103.
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Topics: modeling
Thompson CM , Heintz MM , Cullen JM, Haws LC. 2024. Letter to the Editor of Environmental Pollution: In regard to Wan et al. (2024), “GenX caused liver injury and potential hepatocellular carcinoma of mice via drinking water even at environmental concentration.” Environ Pollut 355(Aug 15):124171; doi: 10.1016/j.envpol.2024.1241741 . PMID: 38776993.
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Topics: Cancer , water
Shirke AV, Radke EG, Lin C, Blain R, Vetter N, Lemeris C, Hartman P,.., Patlewicz G , et al. 2024. Expanded systematic evidence map for hundreds of per- and polyfluoroalkyl substances (PFAS) and comprehensive PFAS human health dashboard. Environ Health Perspect 132(2):026001; doi: 10.1289/EHP134 . PMID: 38319881.
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Topics: PFAS
Racz L, Gauthier A, Bare J, Heintz M , Feifarek D, Kennedy S, Panko J. 2024. Assessment of perfluorocarboxylic acids in fluorinated high-density polyethylene containers and estimation of potential non-cancer risks associated with anticipated use scenarios. Regul Toxicol Pharmacol 147(Feb):105560; doi: 10.1016/j.yrtph.2024.105560 . PMID: 38182014.
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Topics: PFAS
Fitch S, Blanchette A, Haws LC, Franke K, Ring C, DeVito M, Wheeler M,… Wikoff DS . 2024. Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 147(Feb):105571; doi: 10.1016/j.yrtph.2024.105571 . PMID: 38244664.
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Topics: dioxin , Systematic Review
DeVito M, Bokkers B, van Duursen MBM, van Ede K, Feeley M, Antunes Fernandes Gaspar E, Haws L,… Wheeler M,… Wikoff D , et al. 2024. The 2022 World Health Organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Regul Toxicol Pharmacol 146(Jan):105525; doi: 10.1016/j.yrtph.2023.105525 . PMID: 37972849.
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Topics: dioxin , Epidemiology
2023
Wikoff D , Ring C, DeVito M, Walker N, Birnbaum L, Haws L. 2023. Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment. Regul Toxicol Pharmacol 145(Dec):105500; doi: 10.1016/j.yrtph.2023.105500 . PMID: 37866700.
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Topics: dioxin , Epidemiology , risk assessment
Ring C, Blanchette A, Klaren WD , Fitch S , Haws L, Wheeler MW, DeVito MJ, Walker N, Wikoff D . 2023. A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 143(11):105464; doi: 10.1016/j.yrtph.2023.105464 . PMID: 37516304.
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Topics: Bayesian modeling , dioxin
Thompson CM , Brorby G , Keig-Shevlin Z, Smith R, Franzen A , Ulrich K, Blanchette AD, Doepker C. 2023. Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures. Environ Mol Mutagen 64(8–9):420–431; doi: 10.1002/em.22576 . PMID: 37916278.
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