Publications

Chappell GA, Wikoff DS, Doepker CL, Borghoff SJ. 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141(July):111375; doi: 10.1016/j.fct.2020.111375.

Chappell GA, Wikoff DS, Doepker CL, Borghoff SJ. 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141(July):111375; doi: 10.1016/j.fct.2020.111375.

Chappell GA, Britt JK, Borghoff, SJ. 2020. Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes. Food Chem Toxicol 140:111310 [open access].

Rovida C, Barton-Maclaren T, Benfenati E, Caloni F, Chandrasekera PC, Chesne C, Cronin MTD,.., Patlewicz G, et al. 2020. Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology. ALTEX 37(4):579-606; doi: 10.14573/altex.1912181. PMID: 32369604.

Pham LL, Borghoff SJ, Thompson CM. 2020. Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values. Regul Toxicol Pharmacol 113:104651 [open access].

Lea IA, Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK. 2007. Genetic pathways and mutation profiles of human cancers: Site- and exposure-specific patterns. Carcinogenesis 28:1851–1858.

Heintz MM, McRee, R, Kumar, R, Baldwin, WS. 2020. Gender differences in diet-induced steatotic disease in Cyp2b-null mice. PLoS One 15(3):e0229896; doi: 10.1371/journal.pone.0229896. PMID: 32155178.

Wikoff DS, Bennett DC, Brorby GP, Franke KS. 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam Part A; DOI: 10.1080/19440049.2020.1727963.

Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2020. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110898; doi: 10.1016/j.fct.2019.110898.

Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2020. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110898; doi: 10.1016/j.fct.2019.110898.