Publications

de Vries RBM, Angrish M, Browne P, Brozek J, Rooney AA, Wikoff DS, Whaley P, Edwards SW, et al. 2021. Applying evidence-based methods to the development and use of adverse outcome pathways. ALTEX 38(2):336–347; doi: 10.14573/altex.2101211. PMID: 33837437.

Whaley P, Blaauboer BJ, Brozek J, Cohen Hubal EA, Hair K, Kacew S,… , Wikoff D, Woodruff TJ. 2021. Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do. ALTEX 38(3):513-522. doi: 10.14573/altex.2106111. PMID: 34164697.

Dirven H, Vist GE, Bandhakavi S, Mehta J, Fitch SE, Pound P, Ram R, Kincaid B, Leenaars CHC, Chen M, Wright RA, Tsaioun K. 2021. Performance of preclinical models in predicting drug-induced liver injury in humans: A systematic review. Sci Reports 11(1)6403; doi: https://doi.org/10.1038/s41598-021-85708-2. PMID: 33737635.

Chappell GA, Heintz MM, Borghoff SJ, Doepker CL, Wikoff DS. 2021. Lack of potential carcinogenicity for steviol glycosides — Systematic evaluation and integration of mechanistic data into the totality of evidence. Food Chem Toxicol 150(April):112045; doi: 10.1016/j.fct.2021.112045. PMID: 33587976.

Wikoff DS, Urban JD, Ring C, Britt J, Fitch S, Haws LC. 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182; doi: 10.1093/toxsci/kfaa171. PMID: 33306106.

Thompson CM, Bhat VS, Brorby GP, Haws LC. 2021. Development of updated RfD and RfC values for medium carbon range aromatic and aliphatic total petroleum hydrocarbon fractions. J Air Waste Manag Assoc 71(12):1555–1567; doi: 10.1080/10962247.2021.1974123. PMID: 34469276.

Chappell GA, Wikoff DS, Thompson CM. 2021. Assessment of mechanistic data for hexavalent chromium-induced rodent intestinal cancer using the key characteristics of carcinogens. Toxicol Sci 180(1):38–50; doi: 10.1093/toxsci/kfaa187. PMID: 33404626.

Brozek JL, Canelo-Aybar C, Akl EA, Bowen JM, Bucher J, Chiu WA, Cronin M, Djulbegovic B,…, Patlewicz G, et al. 2021. GRADE Guidelines 30: The GRADE approach to assessing the certainty of modeled evidence—An overview in the context of health decision-making. J Clin Epidemiol 129(Jan):138-150; doi: 101016/j.jclinepi.2020.09.018. PMID: 32980429.

Rovida C, Escher SE, Herzler M, Bennekou SH, Kamp H, Kroese DE, Maslankiewicz L, Moné MJ, Patlewicz G, et al. 2021. NAM-supported read-across: From case studies to regulatory guidance in safety assessment. ALTEX 38(1):140-150; doi: 10.14573/altex.2010062. PMID: 33452529.

Chappell GA, Heintz MM, Haws LC. 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41; doi: 10.1016/j.crtox.2021.01.003. PMID: 34345848.