Publications

Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2020. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110898; doi: 10.1016/j.fct.2019.110898. PMID: 31654706.

Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. 2020. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110866; doi: 10.1016/j.fct.2019.110866. PMID: 31614175.

Nelms MD, Pradeep P, Patlewicz G. 2019. Evaluating potential refinements to existing Threshold of Toxicological Concern (TTC) values for environmentally-relevant compounds. Regul Toxicol Pharmacol 109(Dec):104505; doi: 10.1016/j.yrtph.2019.104505. PMID: 31639428.

Helman G, Patlewicz G, Shah I. 2019. Quantitative prediction of repeat dose toxicity values using GenRA. Regul Toxicol Pharmacol 109(Dec):104480; doi: 10.1016/j.yrtph.2019.104480. PMID: 31550520.

Nelms MD, Lougee R, Roberts DW, Richard A, Patlewicz G. 2019. Comparing and contrasting the coverage of publicly available structural alerts for protein binding. Comput Toxicol 12(Nov):100100; doi: 10.1016/j.comtox.2019.100100. PMID: 37701288.

Helman G, Shah I, Patlewicz G. 2019. Transitioning the Generalized Read-Across approach (GenRA) to quantitative predictions: A case study using acute oral toxicity data. Comput Toxicol 12(Nov):1000097; doi: 10.1016/j.comtox.2019.100097. PMID: 33623834.

Chappell G, Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA, Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol 47(7):851-864; doi: 10.1177/0192623319873. PMID: 31558096.

van de Ligt J, Borghoff SJ, Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4)1606-1616; doi: 10.1093/tas/txz153. PMID: 32704923.

Rogers JM, Watanabe M. 2019. Editorial: Special issue on “Developmental effects of smoking, vaping, and cannabis use.” Birth Defects Res 111(17):1245–1247; doi: 10.1002/bdr2.1596. PMID: 31566934.

Yoon M, Ring C, Van Landingham CB, Suh M, Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380(Oct 1):114695; doi: 10.1016/j.taap.2019.114695. PMID: 31394159.