Doepker CD, Heintz MM , van de Ligt JLG, Wikoff DS . 2021. Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits. Trans Anim Sci 5(4):txab203; doi: 10.1093/tas/txab203 . PMID: 34909600.
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Publication: Manuscripts
/ Topics: Food science , nutrition
Wikoff D , Fitch S , Borghoff S . Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff): 61st Annual Meeting of the Society for Birth Defects Research & Prevention, Virtual, June 2021.
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Publication: Abstracts and Presentations
/ Topics: risk assessment
Wikoff D . The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.
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Publication: Abstracts and Presentations
/ Topics: food safety , Food science
Haddadin Z, Rankin DA, Lipworth L, Suh M , McHenry R, Blozinski A, Salib George S, Fernandez KN, et al. 2021. Respiratory virus surveillance in infants across different clinical settings. J Pediat 234(July):p164-p171; doi: 10.1016/j.jpeds.2021.03.036 . PMID: 33774057.
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Publication: Manuscripts
/ Topics: Epidemiology
Fitch SE , Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D . 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Pub Health 21(1):956; doi: 10.1186/s12889-021-10934-2 . PMID: 34016063.
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Publication: Manuscripts
/ Topics: nutrition , Systematic Review
Borghoff SJ , Fitch SE , Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124(Aug):104977; doi: 10.1016/j.yrtph.2021.104977 . PMID: 34174380.
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Publication: Manuscripts
/ Topics: mode of action
Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E… Wikoff D , et al. 2021. Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential. Regul Toxicol Pharmacol 120(March):104859; doi: 10.1016/j.yrtph.2020.104859 . PMID: 33388367.
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Publication: Manuscripts
/ Topics: carcinogens , pharmacology
Kimzey A , Mease K, Mounho-Zamora B, Wood M. 2021. 13. Biosimilar products—A review of past and current regulatory approval standards for preclinical safety studies. In: Translational Medicine : Optimising Preclinical Safety Evaluation of Biopharmaceuticals. CRC Press: Boca Raton, FL .
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Publication: Book Chapters
/ Topics: regulatory toxicology
Houck KA, Patlewicz G , Richard A, Williams AJ, Smeltz M, Clifton, MS, Wetmore B, Medvedev A, Makarov SS. 2021. Bioactivity profiling of per- and polyfluoroalkyl substances identifies potential toxicity pathways related to molecular structure. Toxicology 457(June 15):152789; doi: 10.1016/j.tox.2021.152789 . PMID: 33887376.
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Publication: Manuscripts
/ Topics: PFAS
Proctor DM, Bhat V, Suh M , Reichert H, Jiang X, Thompson CM . 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124(August):104969; doi: 10.1016/j.yrtph.2021.104969 . PMID: 34089813.
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