Wikoff D , Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment
Wikoff D . Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: regulatory toxicology , risk assessment , Systematic Review
Borghoff S , Wikoff D , Urban JD , Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: Cancer , food safety , Food science , mode of action
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
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Publication: Manuscripts
/ Topics: modeling
Klaren WD , Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 . PMID: 28940161.
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Publication: Manuscripts
/ Topics: Metals , PCBs
Suh M , Proctor DM, Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 . PMID: 29689363.
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Publication: Manuscripts
/ Topics: carcinogens , chemical safety assessment , consumer products , genotoxicity , microplastics
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337; doi: 10.1093/toxsci/kfy109 . PMID: 29850908.
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Publication: Letter to the editor
/ Topics: Systematic Review
Patlewicz G , Cronin MTD, Helman G, Lambert JC, Lizarraga LE, Shah I. 2018. Navigating through the minefield of read-across frameworks: A commentary perspective. Comput Toxicol 6(May):39-54; doi: 10.1016/j.comtox.2018.04.002 .
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Publication: Manuscripts
/ Topics: computational toxicology , NAMs
Thompson CM , Wolf JC, Suh M , Proctor DM, Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: carcinogens , chromium
Thompson CM , Suh M , Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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