Wikoff D . Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Borghoff S , Wikoff D , Urban JD , Rager JE . A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342, PMID: 30070899.
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Publication: Manuscripts
/ Topics: Toxicology
Klaren WD , Ring C, Harris MA , Thompson CM , Borghoff S , Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2018. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171, PMID: 30202884.
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Publication: Manuscripts
/ Topics: Toxicology
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Proctor DM. Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA). Thresholds in Toxicology and Risk Assessment Fall Symposium. Oakland, CA,November 14, 2018.
Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium
Thompson CM, Wolf JC, Suh M, Proctor DM , Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018
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Publication: Abstracts and Presentations
/ Topics: Chrome VI
Thompson CM, Suh M, Proctor DM , Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.
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Publication: Abstracts and Presentations
/ Topics: Chrome VI
Proctor, DM . Updating the regulatory risk assessment for hexavalent chromium in California: Implications for regulatory standards. Association of Environmental Health Sciences San Diego, CA, March 20, 2018.
Publication: Abstracts and Presentations
/ Topics: Chrome VI
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings R, Wiench K, Finch L, Proctor DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.