2021
Lizarraga LE, Patlewicz G , Dean JL II, et al. 2021. Provisional Peer-Reviewed Toxicity Values for 3,4-Toluenediamine (CASRN 496-72-0). Cincinnati (OH): U.S. Environmental Protection Agency; Aug. Available from: https://www.ncbi.nlm.nih.gov/books/NBK584583/
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Publication: Report
/ Topics: dose-response , Exposure Assessment
Lizarraga LE, Patlewicz G , Dean JL II, Zhao QJ, Kaiser JP. 2021. Provisional peer-reviewed toxicity values for 3,4-toluenediamine (CASRN 496-72-0). Cincinnati (OH): U.S. Environmental Protection Agency; 2021 Aug. PMID: 36191119.
Publication: Report
/ Topics: chemical safety assessment
Tate T, Wambaugh J, Patlewicz G , Shah I. 2021. Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study. Comput Toxicol 19(Aug):100171; doi: 10.1016/j.comtox.2021.100171 . PMID: 37309449.
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Publication: Manuscripts
/ Topics: transcriptomics
Doepker CD, Heintz MM , van de Ligt JLG, Wikoff DS . 2021. Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits. Trans Anim Sci 5(4):txab203; doi: 10.1093/tas/txab203 . PMID: 34909600.
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Publication: Manuscripts
/ Topics: Food science , nutrition
Wikoff D , Fitch S , Borghoff S . Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff): 61st Annual Meeting (virtual) of the Society for Birth Defects Research & Prevention, June 2021.
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Publication: Abstracts and Presentations
/ Topics: risk assessment
Wikoff D . The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.
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Publication: Abstracts and Presentations
/ Topics: food safety , Food science
Fitch SE , Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D . 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Pub Health 21(1):956; doi: 10.1186/s12889-021-10934-2 . PMID: 34016063.
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Publication: Manuscripts
/ Topics: nutrition , Systematic Review
Borghoff SJ , Fitch SE , Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124(Aug):104977; doi: 10.1016/j.yrtph.2021.104977 . PMID: 34174380.
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Publication: Manuscripts
/ Topics: mode of action
Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E… Wikoff D , et al. 2021. Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential. Regul Toxicol Pharmacol 120(March):104859; doi: 10.1016/j.yrtph.2020.104859 . PMID: 33388367.
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Publication: Manuscripts
/ Topics: carcinogens , pharmacology
Houck KA, Patlewicz G , Richard A, Williams AJ, Smeltz M, Clifton, MS, Wetmore B, Medvedev A, Makarov SS. 2021. Bioactivity profiling of per- and polyfluoroalkyl substances identifies potential toxicity pathways related to molecular structure. Toxicology 457(June 15):152789; doi: 10.1016/j.tox.2021.152789 . PMID: 33887376.
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