2018
Brorby GP . The ongoing controversy surrounding the effects of short-term exposure to trichloroethylene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, San Diego, CA, March 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology , trichloroethylene
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM, Rager JE, Haws LC, Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365; doi: 10.1002/jat.3545 .
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Publication: Manuscripts
/ Topics: Cr(VI) MOA Study , Hexavalent Chromium , pharmacokinetics
Verougstraete V, Henderson R , Mackie C, Newson T, Oller A. 2018. Human health (toxicity) assessment of complex inorganic materials. In: Verougstraete V (ed), Risk Management of Complex Inorganic Materials. Elsevier Inc. ISBN 978-0-12-811063-8 .
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Publication: Book Chapters
/ Topics: Metals
Wikoff D , Urban JD , Harvey S , Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.
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Publication: Manuscripts
/ Topics: risk assessment , Systematic Review , Toxicology , trichloroethylene
2017
Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5)621-640; doi: 10.1002/jat.3412 .
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Publication: Manuscripts
/ Topics: pharmacokinetics , Toxicology
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.
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Publication: Manuscripts
/ Topics: Toxicology
Thompson CM, Suh M , Proctor DM, Haws LC, Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutation Res 823:45-57.
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Publication: Manuscripts
/ Topics: Chrome VI , Hexavalent Chromium
Thompson CM , Young RR, Dinesdurage H, Suh M , Harris MA, Rohr AC, Proctor DM. 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52.
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Publication: Manuscripts
/ Topics: Cr(VI) MOA Study , Hexavalent Chromium
Gadupudi GS, Klaren WD , Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology 56th Annual Meeting, Baltimore, MD, and NIEHS Environmental Health Science FEST, Durham, NC, 2017.
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Publication: Abstracts and Presentations
/ Topics: PCBs , Toxicology
Iwata Y, Klaren WD , Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279; doi; 10.1089/adt.2017.786 . PMID: 28771372.
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