Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG . 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 105838; doi: 10.1016/j.yrtph.2025.105838 . Online ahead of print May 3, 2025. PMID: 40324559.
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Publication: Manuscripts
/ Topics: food additives , food safety , Food science , GRAS , ingredient safety , risk assessment
Brorby G, Franzen A, Thompson C, Wikoff D , Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 115490; doi: 10.1016/j.fct.2025.115490 . Online ahead of print May 2, 2025. PMID: 40320068.
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Publication: Manuscripts
/ Topics: flavorings , food safety , Food science , genotoxicity , risk assessment , safety , Toxicology
Heintz MM , Buerger AN, Haws LC, Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci kfaf049; doi: 10.1093/toxsci/kfaf049 . Online ahead of print 11 April 2025. PMID: 40216583.
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Publication: Manuscripts
/ Topics: mode of action , Toxicology , transcriptomics
Rogers JM, Heintz MM , Haws LC. 2025. Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats. Regul Toxicol Pharmacol 105829; doi: 10.1016/j.yrtph.2025.105829 . Online ahead of print 11 April 2025. PMID: 40222475.
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Publication: Manuscripts
/ Topics: adrenal hypertrophy , industrial solvents , Toxicology
Wikoff D . An introduction to evidence integration. Workshop Session, Abstract 1333, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , NAMs , Toxicology
Wikoff D, Fitch S, Vincent M, Southall MD, Atillasoy E, Weinstein RD, Ejaz SD, Rhoden JD, Choksi N . Biological plausibility assessment of acetaminophen and occurrence of developmental neurological outcomes in humans. Abstract 4768, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025. (Honored as one of the Risk Assessment Specialty Section’s Top 10 Abstracts ).
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Publication: Abstracts and Presentations
/ Topics: acetaminophen i , Toxicology
Thompson CM, Heintz MM , Cullen JM, Haws LC. Evaluation of the chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate (HFPO-DA) in mice. Abstract 4700, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: ammonium , carcinogens , Toxicology
Rogers JM, Heintz MM , Haws LC. Reproduction/developmental toxicity screen and extended one generation reproductive toxicity study of decahydronaphthalene in Sprague Dawley rats. Abstract 3864, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Decahydronaphthalene , Toxicology
Rivera BN, Lea IA, Fitch S , Choksi N, Franzen A , Bus J, Rushton EK, Borghoff SJ . Systematic evaluation of the evidence base on ethyl tert-butyl ether and tert-butyl alcohol for carcinogenic potential in humans: Low concern based on animal cancer studies and mechanistic data. Abstract 4697, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: carcinogens , Cumulative Impact Assessment , ETBE , Exposure Assessment , MTBE , TBA
Proctor D, Thompson C . Why oral cavity tumors should not be the basis of the hexavalent chromium oral cancer slope factor-weight of evidence review. Abstract 3136, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025. (Honored as one of the Risk Assessment Specialty Section’s Top 10 Abstracts ).
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