Heintz MM , Chappell GA, Thompson CM , Haws LC. 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
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Publication: Manuscripts
/ Topics: PFAS , transcriptomics
Goyak KO, Sarang SS, Franzen A , Borghoff SJ , Ryman-Rasumssen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol, online open access .
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Publication: Manuscripts
/ Topics: Toxicology
Foster MJ, Patlewicz G , Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245 . PMID: 37841081.
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Publication: Manuscripts
/ Topics: NAMs
Henderson RG , Nguyen H. 2022. Pathways to the US supplement market: New Dietary Ingredient notification and Generally Recognized as Safe determination. Chapter 19 in: Ruthsatz M, Wong AW (eds), Nutrition, Health, and Disease: Regulatory Policy Matters. Regulatory Affairs Professionals Society (RAPS), online store .
Publication: Book Chapters
/ Topics: Toxicology
Doepker C, Movva N, Cohen SS, Wikoff DS . 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol 170(Dec):113472; doi: 10.1016/j.fct.2022.113472 . PMID: 36243217.
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Publication: Manuscripts
/ Topics: Exposure Assessment , Food science , Systematic Review , Toxicology
Patlewicz G , Richard A, Williams A, Judson R, Thomas R. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Patlewicz G , Shah I. Towards systematic read-across using Generalised Read-Across (GenRA). American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: read-across
Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G , et al. 2022. Estimating provisional margins of exposure for data poor chemicals using high throughput computational methods. Front Pharmacol 13(Oct 7):980747; doi: 10.3389/fphar.2022.980747 . PMID: 36278238.
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Publication: Manuscripts
/ Topics: computational toxicology
Carstens K, Carpenter A, FreudenrichT, Wallace K, Choo S, Patlewicz G , et al. Evaluation of per- and poly fluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study in using graph kernels and predicted metabolism information. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022