Heintz MM , Chappell GA, Thompson CM , Haws LC. 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
View Abstract
Publication: Manuscripts
/ Topics: PFAS , transcriptomics
Goyak KO, Sarang SS, Franzen A , Borghoff SJ , Ryman-Rasumssen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol 52(5):345-357; doi: 10.1080/10408444.2022.2082269 . PMID: 35862579.
View Abstract
Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs)
Foster MJ, Patlewicz G , Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245 . PMID: 37841081.
View Abstract
Publication: Manuscripts
/ Topics: NAMs
Patlewicz G , Richard A, Williams A, Judson R, Thomas R. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Patlewicz G , Shah I. Towards systematic read-across using Generalised Read-Across (GenRA). American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: read-across
Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G , et al. 2022. Estimating provisional margins of exposure for data poor chemicals using high throughput computational methods. Front Pharmacol 13(Oct 7):980747; doi: 10.3389/fphar.2022.980747 . PMID: 36278238.
View Abstract
Publication: Manuscripts
/ Topics: computational toxicology
Carstens K, Carpenter A, FreudenrichT, Wallace K, Choo S, Patlewicz G , et al. Evaluation of per- and poly fluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study in using graph kernels and predicted metabolism information. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022
Publication: Abstracts and Presentations
/ Topics: read-across
Reichert H, Suh M , Jiang X, Movva N, Bylsma LC, Fryzek JP, Nelson CB. 2022. Mortality associated with respiratory syncytial virus, bronchiolitis, and influenza among infants in the United States: A birth cohort study from 1998 to 2018. J Infect Dis 226(Suppl 2):S246–S254; doi: 10.1093/infdis/jiac127 . PMID: 35968877.
View Abstract
Publication: Manuscripts
/ Topics: Epidemiology
Bylsma LC, Suh M, Movva N, Fryzek JP, Nelson CB. 2022. Mortality among United States infants and children under 5 years of age with respiratory syncytial virus and bronchiolitis: A systematic literature review. J Infect Dis 226(Suppl 2):S267–S281; doi: 10.1093/infdis/jiac226 . PMID: 35968871.
View Abstract