Publication Topic

Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152. PMID: 39792025.

Wikoff D. Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Wikoff D. Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA. 2025. Systematic evaluation of the evidence base on methyl tert-butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224. PMID: 40084233.

Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE. 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030. PMID: 39873747.

Firman JW, Boobis A, Hollnagel HM, Kaiser S, Lovell DP, Moretto A, Muller S,…, Patlewicz G. 2024. Evaluating the consistency of judgements derived through both in silico and expert application of the Cramer classification scheme. Food Chem Toxicol 194(Dec):115070; doi: 10.1016/j.fct.2024.115070. PMID: 39447833.

Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D. 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723.

Lynn SG, Lea IA, Urban J, Borghoff SJ, Wikoff D, Fitch S, Perry C, Choksi N, Britt J, Heintz M, Klaren W, et al. Development and application of systematic approach to inventory and interrogate thyroid hormone network information. Abstract 4357, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

Allen B, Vincent M, Lipworth L, Panko J, Suh M, Jiang X, Mumma MT, Proctor D. Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Poster presentation at Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Chang D, Cowden J, Davidson-Fritz S, Dean J, Devito M, Everett L, Harrill A,.., Patlewicz G, et al. 2024. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). EPA/600/X-23/084. U.S. Environmental Protection Agency: Washington, DC; doi: 10.23645/epacomptox.25365550.