2023
Racz L, Mittal L , Perry CS , Blanchette A, Proctor D. Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44th Annual Meeting, Louisville, KY, November 2023.
Publication: Abstracts and Presentations
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Publication: Manuscripts
2022
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY… Wikoff D , et al. 2022. Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX 39(3):499-518; doi: 10.14573/altex.2202141 .
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Publication: Manuscripts
2021
Thompson CM , Aardema MJ, Heintz MM , MacGregor JT, Young RR. 2021. A review of mammalian in vivo genotoxicity of hexavalent chromium: Implications for oral carcinogenicity risk assessment. Crit Rev Toxicol 51(10)820-849; doi: 10.1080/10408444.2021.2000934 . PMID: 35060824.
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Publication: Manuscripts
Proctor DM , Bhat V, Suh M , Reichert H , Jiang X , Thompson CM . 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124(August):104969; doi: 10.1016/j.yrtph.2021.104969 . PMID: 34089813.
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Publication: Manuscripts
2018
Wikoff D , Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
Wikoff D , Urban JD , Harvey S , Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.
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Publication: Manuscripts
2017
Chappell G, Welsh B, Harvey S, Harris M, Wikoff D . Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Publication: Abstracts and Presentations
2015
Thompson CM , Suh M , Hixon G, Bichteler A. 2015. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, March 2015.
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Publication: Abstracts and Presentations
2014
Thompson CM , Proctor DM, Suh M, Wolf JC, Haws LC,Seiter JM, Chappell MA, Harris MA. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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