2024
Allen B, Vincent M, Lipworth L, Panko J, Suh M , Jiang X, Mumma MT, Proctor D. Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Poster presentation at Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
Publication: Abstracts and Presentations
Chang D, Cowden J, Davidson-Fritz S, Dean J, Devito M, Everett L, Harrill A,.., Patlewicz G , et al. 2024. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). EPA/600/X-23/084. U.S. Environmental Protection Agency: Washington, DC; doi: 10.23645/epacomptox.25365550 .
Publication: Report
Brennan A, Chang D, Cowden J, Davidson-Fritz S, Dean J, Devito M, Ford J, … , Patlewicz G , et al. 2024. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. EPA/600/X-24/066. U.S. Environmental Protection Agency: Washington, DC; doi: 10.23645/epacomptox.25352962 .
Publication: Report
2023
Wikoff D , Ring C, DeVito M, Walker N, Birnbaum L, Haws L. 2023. Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment. Regul Toxicol Pharmacol 145(Dec):105500; doi: 10.1016/j.yrtph.2023.105500 . PMID: 37866700.
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Publication: Manuscripts
Racz L, Mittal L , Perry CS , Blanchette A, Proctor D. Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44th Annual Meeting, Louisville, KY, November 2023.
Publication: Abstracts and Presentations
Bowden A, Escher S, Rose J, Sadekar N, Patlewicz G , O’Keeffe L, Bury D, Hewitt NJ, et al. 2023. Workshop report: Challenges faced in developing inhalation Thresholds of Toxicological Concern (TTC) – State of the science and next steps. Regul Toxicol Pharmacol 142(Aug):105434; doi: 10.1016/j.yrtph.2023.105434 . PMID: 37302561.
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Publication: Manuscripts
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Publication: Manuscripts
Thompson CM, Wikoff DS , Proctor DM, Harris MA. An evaluation of risk assessments on hexavalent chromium [Cr(VI)]: The past, present, and future of mode of action research. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
Franzen AC, Thompson CM, Brorby GP , Wikoff DS , Ilkbahar Z, Doepker C. Risk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
East A, Rish W, Klaren WD . Using NHANES data to characterize the magnitude of allostatic load in vulnerable communities: Impact to existing risk assessment uncertainty/variability factors. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.