Publications

Lefever TW, Trexler KR, Henderson RG, Bonn-Miller MO. Pre-clinical evaluation of cannabidiol toxicity in rats. Poster at the 32nd Annual International Cannabinoid Research Society Symposium on the Cannabinoids [presented by TL], Galway, Ireland, June 2022.

Henderson RG, Lefever TW, Heintz MM, Trexler KR, Borghoff SJ, Bonn-Miller MO. 2023. Oral toxicity evaluation of cannabidiol. Food Chem Toxicol 176:113786.

Henderson RG, Welsh BT, Rogers JM, Borghoff SJ, Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Reproductive and developmental toxicity evaluation of cannabidiol. Food Chem Toxicol 176:113786.

Henderson RG, Welsh BT, Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Genotoxicity evaluation of cannabidiol. Regul Toxicol Pharmacol 142:105425.

Kulpa J, Lefever TW, Trexler KR, Henderson R, MacNair L, Toth ML, Vanapalli SA, Rahman M, Gupta S, Bonn-Miller MO. 2023. Toxicity of cannabigerol (CBG): Examination of long-term toxicity and lifespan in Caenorhabditis elegans & 14-day study in Sprague Dawley rats. Cannabis Cannabinoid Res (in press); abstract only, ahead of print.

Rivera BN, Svetlik A, Klaren WD, Wikoff DS, Henderson RG. Scoping review of the immunomodulatory effects of cannabidiol: Effects within T cells. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

Klaren WD, Heintz MM, East AW, Thompson CM, Haws LC. In vitro transcriptomic analyses informing the mode of action of HFPO-DA (GenX) in the liver. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

East A, Rish W, Klaren WD. Using NHANES data to characterize the magnitude of allostatic load in vulnerable communities: Impact to existing risk assessment uncertainty/variability factors. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

Thompson CM, Heintz MM, Wolf JC, Cheru R, Haws LC, Cullen JM. 2023. Assessment of mouse liver histopathology following exposure to HFPO-DA with emphasis on understanding mechanisms of hepatocellular death. Toxicol Pathol 51(1–2):4–14; doi: 10.1177/01926233231159078.

Heintz MM, Haws LC, Klaunig JE, Cullen JM, Thompson CM. 2023. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans. Toxicol Sci 192(1):15–29; doi: 10.1093/toxic/kfad004.