Publications

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology, Central States Regional Meeting, Iowa City, IA, 2016. Also presented at NIEHS Obesity Grantee Meeting and 25 Years of Endocrine Disruption Workshop, NIH, Bethesda, MD, 2016.

Klaren WD, Vine D, Vogt S, Robertson LW. Evaluation of the spatial distribution of hepatic metals following PCB126 exposure with x-ray fluorescence microscopy. Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.

Klaren WD, Iwata Y, Lebakken CS, Grimm FA, Rusyn I. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. College of Veterinary Medicine Graduate Student and Postdoc Research Symposium, Texas A&M University, 2016.

Borghoff SJ. Organization and review of mechanistic data according to “Ten Key Characteristics of Carcinogens” (TKCC) {Smith et al., 2016}. Presented at the 42^nd Annual Summer Meeting of the Toxicology Forum, Salt Lake City, UT, July 2016.

Samuel GO, Hoffmann S, Wright R, Lalu MM, Patlewicz G, Becker RA, DeGeorge GL, Fergusson D, et al. 2016. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review. Environ Int 92-93(July-Aug):630-646; doi: 10.1016/j.envint.2016.03.010. PMID: 27039952.

Wang BW, Klaren WD, Wels B, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. 2016. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicol Sci 150(1):15–26; doi: 10.1093/toxsci/kfv312. PMID: 26660635.

Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. 2016. Assessment of the mitigative capacity of dietary zinc on PCB126 hepatotoxicity and the contribution of zinc to toxicity. Chem Res Toxicol 29(5):851–859; 10.1021/acs.chemrestox.6b00022. PMID: 26967026.

Klaren WD, Flor SS, Gibson-Corley KN, Ludewig G, Robertson LW. 2016. Metallothionein’s role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption. Toxicol Rep 3:21–28; doi: 10.1016/j.toxrep.2015.12.001. PMID: 26770886.

Wikoff DS, Rager JE, Haws LC, Borghoff SJ. 2016. A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework. Regul Toxicol Pharmacol 77(June):143-159. doi: 10.1016/j.yrtph.2016.01.018. PMID: 26828025.

Hanlon P, Brorby GP, Krishan M. 2016. A risk-based strategy for evaluating mitigation options for processed-formed compounds in food: Workshop proceedings. Int J Toxicol 35(3):358–370; doi: 10.1177/1091581816640. PMID: 27102178.