2024
Allen B, Vincent M , Lipword L, Panko J , Suh M , Jiang X , Mumma, Proctor D . Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.
Publication: Abstracts and Presentations
2023
Thompson CM , Kirman C, Harris MA . 2023. Derivation of oral cancer slope factors for hexavalent chromium informed by pharmacokinetic models and in vivo genotoxicity data. Regul Toxicol Pharmacol 145:105521.
View Abstract
Publication: Manuscripts
Thompson CM , Proctor DM , Harris MA . 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 .
Publication: Manuscripts
2021
Proctor DM , Bhat V, Suh M , Reichert H , Jiang X , Thompson CM . 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124:104969, doi.org/10.1016/j.yrtph.2021.104969.
View Abstract
Publication: Manuscripts
2020
Wikoff D , Franzen A , Chappell G, Harris M , Thompson C . Systematic characterization of hexavalent chromium and potential female reproductive outcomes: Application of US EPA critical appraisal tools and stepwise inclusion of mechanistic data. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
View Abstract
Publication: Abstracts and Presentations
2019
Suh M , Wikoff D , Lipworth L, Goodman M, Fitch S , Mittal L , Ring C, Proctor D . 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol [ePub ahead of print]: doi: 10.1080/10408444.2019.1578730.
View Abstract
Publication: Manuscripts
2018
Proctor DM. Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA). Thresholds in Toxicology and Risk Assessment Fall Symposium. Oakland, CA,November 14, 2018.
Publication: Abstracts and Presentations
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE, Proctor DM , Rager JE , Haws LC , Harris MA . 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545.
View Abstract
Publication: Manuscripts
2017
Thompson CM, Suh M, Proctor DM, Haws LC, Harris MA . 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutation Res 823:45-57.
View Abstract
Publication: Manuscripts
Thompson CM , Young RR, Dinesdurage H, Suh M , Harris MA , Rohr AC, Proctor DM . 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52.
View Abstract