2017
Iwata Y, Klaren W , Grimm F, Rusyn I. A multidimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
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Publication: Abstracts and Presentations
/ Topics: chemical safety assessment , Exposure Assessment
Fitzpatrick JM, Roberts DW, Patlewicz G . 2017. What determines skin sensitization potency–Myths, maybes and realities. The 500 molecular weight cut-off – An updated analysis. J Appl Toxicol 37(1):105-116; doi: 10.1002/jat.3348 . PMID: 27283458.
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Publication: Manuscripts
/ Topics: Exposure Assessment
Fitzpatrick JM, Roberts DW, Patlewicz G . 2017. Is skin penetration a determining factor in skin sensitization potential and potency? Refuting the notion of a LogKow threshold for skin sensitization. J Appl Toxicol 37(1):117-127; doi: 10.1002/jat.3354 . PMID: 27357739.
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Publication: Manuscripts
/ Topics: Exposure Assessment
Lea IA , Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077 . PMID: 27899660.
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Publication: Manuscripts
/ Topics: computational toxicology
2016
Patlewicz G , Casati S, Basketter D, Asturiol D, Roberts DW, Lepoittevin J-P, Aschberger K. 2016. Can currently available non-animal methods detect pre and pro haptens relevant for skin sensitization? Regul Toxicol Pharmacol 82(10):147-155;p doi: 10.1016/j.yrtph.2016.08.007 . PMID: 27569201.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs)
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57(9):706-716; doi: 10.1002/em.22064 . PMID: 27859739.
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Publication: Manuscripts
/ Topics: chromium , risk assessment , transcriptomics
Wikoff D, Suh M, Harvey S , Proctor D, Beretvas T, Goodman M, Lipworth L. 2016. Systematic review and meta-analysis of occupational exposure to Cr(VI) and stomach cancer. PROSPERO 2016:CRD42016051625 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016051625
Publication: Protocol Registrations
/ Topics: Cancer , chromium , meta-analysis , Occupational , Systematic Review
Roberts DW, Api AM, Patlewicz G , Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007 . PMID: 27424000.
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Publication: Manuscripts
/ Topics: computational toxicology
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 . PMID: 27233922.
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