2019

Patlewicz G, Lizarraga L, Rua D, Allen DG, Daniel A, Fitzpatrick SC, Garcia-Reyero N, Gordon J, et al. 2019. Exploring current read-across applications and needs among selected US federal agencies. Regul Toxicol Pharmacol 106(Aug):197-209; doi: 10.1016/j.yrtph.2019.05.011. PMID: 31078681.

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Fitch S, van de Ligt J, Payne L, Doepker C, Kleinman R, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2019. Systematic map protocol: A systematic map of the use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS). Open Science Framework.

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Sheridan E, Moose J, Liu Y, Martini C, Lea I, Fostel J. NTP high-level summary data collections in the Chemical Effects in Biological Systems (CEBS) database. Poster PS01-0606. Presented at 15th International Congress of Toxicology, Honolulu, HI, July 2019.

Olack E, Heintz MM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme involved in unsaturated fatty acid metabolism. International Congress on Toxicology (ICTXV), Honolulu, HI, July 2019.

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2019. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171; doi: 10.1093/toxsci/kfy220. PMID: 30202884.

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Bhawana B, Lea I, Liu Y, Martini C, Fostel J. Access to National Toxicology Program histopathology lesion collection in Chemical Effects in Biological Systems (CEBS) database. Poster P040. Presented at the 38th Annual Symposium of Society for Toxicologic Pathology, Raleigh, NC, June 2019.

Urban J, Wikoff D, Haws L. Three-tiered approach to integrating evidence streams assessing gestational trichloroethylene exposure and congenital heart defects (TCE-CHD). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions, National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Thomas RS, Bahadori T, Buckley T, Cowden J, Deisenroth C, Dionisio K, Frithsen J,…, Patlewicz G, et al. 2019. The next generation of computational toxicology at the US Environmental Protection Agency. Toxicol Sci 169(2):317-332; doi: 10.1093/toxsci/kfz058. PMID: 30835285.

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Rager JE, Suh M, Chappell G, Thompson CM, Proctor DM. 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305(May 1):40-50; doi: 10.1016/j.toxlet.2019.01.011. PMID: 30690063.

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Heintz MM, McRee R, Baldwin WS. The role of Cyp2b in diet-induced nonalcoholic steatohepatitis. Invited speaker: Clemson University Environmental Toxicology Program Seminar, Clemson, SC, April 2019.