2019
Thompson C , Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.
Publication: Abstracts and Presentations
/ Topics: PFAS
Chappell GA, Thompson CM , Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.
Publication: Abstracts and Presentations
/ Topics: PFAS , transcriptomics
Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C , Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106(Aug):210–223; doi: 10.1016/j.yrtph.2019.04.015 .
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Publication: Manuscripts
/ Topics: formaldehyde , risk assessment
Clewell RA, Thompson CM , Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March):112–127; doi: 10.1016/j.cbi.2019.01.025 .
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Publication: Manuscripts
/ Topics: carcinogens , risk assessment
van de Ligt J, Borghoff SJ , Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4)1606-1616; doi: 10.1093/tas/txz153 .
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Publication: Manuscripts
/ Topics: Food science
Thompson CM , Fitch SE , Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39(9):1267–1282; doi: 10.1002/jat.3812 .
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , PFAS , water
Yoon M, Ring C, Van Landingham CB, Suh M , Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695
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Publication: Manuscripts
/ Topics: Toxicology
Fitch S, Goyak K, Green Maia, Grimm F, Wikoff D . 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework , August.
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Publication: Protocol Registrations
/ Topics: Systematic Review
Webster F, Gagne M, Patlewicz G , Pradeep P, Trefiak N, Judson R, Barton-Maclaren TS. 2019. Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study. Regul Toxicol Pharmacol 106(Aug):278-291; doi: 10.1016/j.yrtph.2019.05.017 . PMID: 31121201.
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Publication: Manuscripts
/ Topics: NAMs
Patlewicz G , Lizarraga L, Rua D, Allen DG, Daniel A, Fitzpatrick SC, Garcia-Reyero N, Gordon J, et al. 2019. Exploring current read-across applications and needs among selected US federal agencies. Regul Toxicol Pharmacol 106(Aug):197-209; doi: 10.1016/j.yrtph.2019.05.011 . PMID: 31078681.
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