Publications

Borghoff SJ, Fitch S, Huggett D, Wikoff D. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Lea I, Liu Y, Sheridan E, Motti D, Martini C, Fostel J, Auerbach S. Hallmark gene set annotation for NTP toxicogenomic studies. Abstract #1743-P119, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I, Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Abstract #1749-P125, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Wikoff D. Rigor and resources for systematic reviews in toxicology: Case study applications in food safety, consumer product safety, and environmental health risk assessment. Presented at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March 1):112–127; doi: 10.1016/j.cbi.2019.01.025. PMID: 30763550.

Wikoff D, Fitch SE, Payne L, Doepker C, van de Ligt J. 2019. Systematic map: Use of the acceptable daily intake (ADI) values in nutrition research studies that consider the safety of low-calorie sweeteners. Open Science Framework.

Pradeep P, Carlson LM, Judson R, Lehmann GM, Patlewicz G. 2019. Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls. Regul Toxicol Pharmacol 101(Feb):12-23; doi: 10.1016/j.yrtph.2018.10.013. PMID: 30359698.

Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, Ring C, Proctor D. 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol 49(2):140-159; doi: 10.1080/10408444.2019.1578730. PMID: 30896278.

Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335; doi: 10.1093/toxsci/kfy279. PMID: 30423162.