2025
Rogers JM , Buerger AN, Heintz MM, Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
View Abstract
Topics: phthalates
Lea IA , Buerger AN, Feifarek D, Mihalchik A, Heintz MM, Haws LC, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461. Corrigendum 8:100233; doi: 10.1016/j.crtox.2025.100233 ; PMID 40529321.
View Abstract
Topics: phthalates
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
View Abstract
Topics: ecotoxicology , risk assessment
Patlewicz G , Williams AJ, Adams M, Shah I, Paul-Friedman K. 2025. A cheminformatics workflow to select representative TSCA chemicals for New Approach Methodology (NAM) screening. Chem Res Toxicol 38(1):129-144; doi: 10.1021/acs.chemrestox.4c00367 . PMID: 39655894.
View Abstract
Topics: NAMs
Lipworth L, Panko JM, Allen BC, Mumma MT, J iang X, Vincent MJ, Bare JL, Antonijevic T, Vivanco SN, Marano DE, Suh M , Cohen S, Mittal L , Proctor DM. 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
View Abstract
Topics: Cancer , chromium , Exposure Assessment , Occupational
2024
Firman JW, Boobis A, Hollnagel HM, Kaiser S, Lovell DP, Moretto A, Muller S,…, Patlewicz G . 2024. Evaluating the consistency of judgements derived through both in silico and expert application of the Cramer classification scheme. Food Chem Toxicol 194(Dec):115070; doi: 10.1016/j.fct.2024.115070 . PMID: 39447833.
View Abstract
Topics: risk assessment
Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D . 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723 .
View Abstract
Topics: Food science , nutrition , risk assessment
Banerjee A, Kar S, Roy K, Patlewicz G , Charest N, Benfenati E, Cronin MTD. 2024. Molecular similarity in chemical informatics and predictive toxicity modeling: From quantitative read-across (q-RA) to quantitative read-across structure-activity relationship (q-RASAR) with the application of machine learning. Crit Rev Toxicol 54(9):659-684; doi: 10.1080/10408444.2024.2386260 . PMID: 39225123.
View Abstract
Topics: modeling
Perry CS , Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 . PMID: 39251127.
View Abstract
Topics: Air Quality , Manganese , modeling , PBPK/PBDE
Patlewicz G , Judson RS, Williams AJ, Butler T, Barone Jr. S, Carstens K, Cowden J, Dawson JD, et al. 2024. Development of chemical categories for per- and polyfluoroalkyl substances (PFAS) and the proof-of-concept approach to the identification of potential candidates for tiered toxicological testing and human health assessment. Comput Toxicol 131(Sep 1):100327; doi: 10.1016/j.comtox.2024.100327 . PMID: 40547594.
View Abstract