DeVito, Bokkers B, van Duursen M, van Ede K, Feeley M,… Haws L,… Wikoff D , et al. The 2022 WHO reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Abstract 3626, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
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Topics: dioxin
Thompson CM , Heintz MM , Rogers SI, Fitch SE , Rivera BN, Klaren WD , Vincent MJ, Wikoff DS , Haws LC. Evidence identification and appraisal supporting development of an updated toxicity value for HFPO-DA. Abstract 3654, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
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Topics: evidence-based reviews , PFAS
Heintz M , Klaren W , East A, Haws L, Thompson C . Delayed transcriptomic responses in PPARa knockout mouse hepatocytes compared to wild-type hepatocytes exposed to HFPO-DA or PPARa agonist GW7647: Support for a PPARa-dependent mode of action for HFPO-DA in mouse hepatocytes. Abstract 4100, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
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Topics: transcriptomics
Petrick J, Mihalchik A , Tiwary A, Kreidl L, Swartz C, Bhattarai N. Nonclinical safety evaluation of 1-monoacetin and 2-monoacetin as potential impurities in pharmaceutical excipients. Abstract 3107, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
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Topics: nonclinical safety assessment , pharmacology
Franke K, Vincent M, Rogers S, Rivera B, Wikoff D . Assessment of non-occupational exposures to cleaning products and the incidence of asthma and respiratory disease. Abstract 3393, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.
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Topics: chemical safety assessment , Exposure Assessment
Patlewicz G . Comparing expert-driven read-across assessments using the generalized read-across framework. Abstract 1110, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.