2018
Borghoff S , Wikoff D , Urban JD , Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: Cancer , food safety , Food science , mode of action
Thompson CM , Wolf JC, Suh M , Proctor DM, Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: carcinogens , chromium
Thompson CM , Suh M , Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: chromium , mode of action
Brorby GP . The ongoing controversy surrounding the effects of short-term exposure to trichloroethylene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, San Diego, CA, March 2018.
Topics: trichloroethylene
Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I , Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Abstract 2525-P887, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: computational toxicology
Heintz MM , Kumar R, Baldwin WS. The role of Cyp2b in the metabolism of unsaturated fatty acids. Abstract #1291, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: metabolites
McRee R, Heintz MM , Baldwin WS. Inhibition of CYP2B6 does not necessarily alter toxicity except in the case of chemicals with known active metabolites. Abstract #1292, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Topics: metabolites
Klaren WD , Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
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Topics: regulatory toxicology
2017
Jackson M, Yang L, Yauk CL, Lea I , Kuo B, Williams A, Rashid A, Fostel J. The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals. Abstract 1224. Presented at the 48th Annual Meeting of Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 2017.
Topics: biomarkers
Gadupudi GS, Klaren WD , Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology 56th Annual Meeting, Baltimore, MD, and NIEHS Environmental Health Science FEST, Durham, NC, 2017.
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