Patlewicz G , Paul Friedman K, Houck K, Zhang L, Huang R, Xia M, Brown J, Simmons SO. 2023. Evaluating the utility of a high throughput thiol-containing fluorescent probe to screen for reactivity: A case study with the Tox21 library. Comput Toxicol 26(May):100271; doi: 10.1016/j.comtox.2023.100271 . PMID: 37388277.
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Publication: Manuscripts
/ Topics: modeling
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Publication: Manuscripts
/ Topics: risk assessment
Klaren WD, Heintz MM, East AW, Thompson CM, Haws LC. In vitro transcriptomic analyses informing the mode of action of HFPO-DA (GenX) in the liver. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: transcriptomics
East A, Rish W, Klaren WD . Using NHANES data to characterize the magnitude of allostatic load in vulnerable communities: Impact to existing risk assessment uncertainty/variability factors. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: community health , NHANES , risk assessment
Rivera BN, Svetlik A, Klaren WD , Wikoff DS , Henderson RG . Scoping review of the immunomodulatory effects of cannabidiol: Effects within T cells. Poster presented at Society of Toxicology Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: Systematic Review
Thompson CM , Heintz MM , Wolf JC, Cheru R, Haws LC, Cullen JM. 2023. Assessment of mouse liver histopathology following exposure to HFPO-DA with emphasis on understanding mechanisms of hepatocellular death. Toxicol Pathol 51(1–2):4–14; doi: 10.1177/01926233231159078 . PMID: 36987989.
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Publication: Manuscripts
/ Topics: ammonium , Exposure Assessment , PFAS
Heintz MM , Haws LC, Klaunig JE, Cullen JM, Thompson CM . 2023. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans. Toxicol Sci 192(1):15–29; doi: 10.1093/toxic/kfad004 . PMID: 36629480.
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Publication: Manuscripts
/ Topics: Cancer , mode of action , PFAS
Choksi NY, Fitch S, Harris MA, Thompson CM , Wikoff DS . Reliability assessment of guideline-based studies using systematic review critical appraisal tools. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: Systematic Review
Richard AM, Lougee R, Adams M, Hidle H, Yang C, Rathman J, Magdziarz T, Bienfait B, Williams AJ, Patlewicz G . 2023. A new CSRML structure-based fingerprint method for profiling and categorizing per- and polyfluoroalkyl substances (PFAS). Chem Res Toxicol 36(3):508–534; doi: 10.1021/acs.chemrestox.2c00403 . PMID: 36862450.
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Publication: Manuscripts
/ Topics: PFAS
Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS,…, Patlewicz G , et al. 2023. Evaluation of per- and polyfluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. Chem Res Toxicol 36(3):402–419; doi: 10.1021/acs.chemrestox.2c00344 . PMID: 36821828.
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