Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5)621-640; doi: 10.1002/jat.3412 .
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Publication: Manuscripts
/ Topics: pharmacokinetics , Toxicology
Thompson CM , Bichteler A, Rager JE, Suh M , Proctor DM, Haws LC, Harris MA. 2016. Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium. Mut Res/Genet Toxicol Environ Mutagen 800-801(April):28-34; doi: 10.1016/j.mrgentox.2016.01.008 .
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Publication: Manuscripts
/ Topics: carcinogens , chromium , mode of action
Patlewicz G , Casati S, Basketter D, Asturiol D, Roberts DW, Lepoittevin J-P, Aschberger K. 2016. Can currently available non-animal methods detect pre and pro haptens relevant for skin sensitization? Regul Toxicol Pharmacol 82(10):147-155;p doi: 10.1016/j.yrtph.2016.08.007 . PMID: 27569201.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs)
Bichteler A . 2016. Constrained multiple imputation: A case study in estimation and modeling on data missing below the limit of detection. Presented in the “Melding Dose-Response Relationships” session at the Society of Risk Analysis, December 14, San Diego, CA.
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Publication: Abstracts and Presentations
Wikoff D, Suh M, Harvey S , Proctor D, Beretvas T, Goodman M, Lipworth L. 2016. Systematic review and meta-analysis of occupational exposure to Cr(VI) and stomach cancer. PROSPERO 2016:CRD42016051625 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016051625
Publication: Protocol Registrations
/ Topics: Chrome VI , Systematic Review
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57:706-716.
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Publication: Manuscripts
/ Topics: Chrome VI , Cr(VI) MOA Study , Hexavalent Chromium
De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M , Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmaco l 306:113-119.
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Publication: Manuscripts
/ Topics: Chrome VI , Cr(VI) MOA Study
Rager J, Thompson C, Auerbach S, Fry R. 2016. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, September 25, Kansas City, KS.
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Publication: Abstracts and Presentations
Roberts DW, Api AM, Patlewicz G , Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007 . PMID: 27424000.
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