2019
Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I , Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Presented at the 58th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2019. Abstract #1749-P125.
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Publication: Abstracts and Presentations
2018
Kimzey AL , Piche M-S, Wood M , Weir AB, Lansita J . 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427 .
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Publication: Book Chapters
Tsaioun K, Dirven H, Beck Færden K, Wikoff D , Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S . 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353 .
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Publication: Manuscripts , Protocol Registrations
Borghoff SJ, Fitch S , Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99:168–181.
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Publication: Manuscripts
Grimm FA, Klaren WD , Li X, House JS, Chiu W, Lehmler HJ, Robertson LW, Rusyn I. Cardiotoxicity screening of polychlorinated biphenyls and their major metabolites. Society of Toxicology Annual Meeting, San Antonio, Tx (presenter), 2018.
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Publication: Abstracts and Presentations
Klaren WD , Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology Annual Meeting, San Antonio, Tx, 2018.
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Publication: Abstracts and Presentations
Borghoff S , Wikoff D , Urban JD , Rager JE . A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.
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Publication: Abstracts and Presentations
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342, PMID: 30070899.
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Publication: Manuscripts
Klaren WD , Ring C, Harris MA , Thompson CM , Borghoff S , Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2018. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171, PMID: 30202884.
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