2016
Roberts DW, Api AM, Patlewicz G , Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007 . PMID: 27424000.
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Topics: computational toxicology
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 . PMID: 27233922.
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Topics: Air Quality , mode of action , Systematic Review
De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M , Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmaco l 306(Sept 1):113-119; doi: 10.1016/j.taap.2016.07.004 . PMID: 27404458.
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Topics: chromium
Kirman CR, Suh M , Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC, Harris MA, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling. Toxicol Appl Pharmacol 306(Sep 1):120-133; doi: 10.1016/j.taap.2016.07.002 . PMID: 27396814.
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Topics: chromium
Richard A, Judson R, Houck K, Grulke C, Volarath P, Thillainadarajah I, Yang C,…, Patlewicz G , et al. 2016. The ToxCast chemical landscape: Paving the road to 21st century toxicology. Chem Res Toxicol 29(8):1225-1251; doi: 10.1021/acs.chemrestox.6b00135 . PMID: 27367298.
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Topics: computational toxicology
Suh M , Thompson CM , Brorby GP , Mittal L , Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(Aug):74-82; doi: 10.1016/j.yrtph.2016.05.009 . PMID: 27177823.
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Topics: Cancer , cobalt , Metals , risk assessment
Shah I, Liu J, Judson RS, Thomas R, Patlewicz G . 2016. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. Reg Toxicol Pharmacol 79(Aug):12-24; doi: 10.1016/j.yrtph.2016.05.008 . PMID: 27174420.
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Topics: read-across
Samuel GO, Hoffmann S, Wright R, Lalu MM, Patlewicz G , Becker RA, DeGeorge GL, Fergusson D, et al. 2016. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review. Environ Int 92-93(July-Aug):630-646; doi: 10.1016/j.envint.2016.03.010 . PMID: 27039952.
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Topics: scoping review
Wang BW, Klaren WD , Wels B, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. 2016. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicol Sci 150(1):15–26; doi: 10.1093/toxsci/kfv312 . PMID: 26660635.
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Topics: Manganese , PCBs
Klaren WD , Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. 2016. Assessment of the mitigative capacity of dietary zinc on PCB126 hepatotoxicity and the contribution of zinc to toxicity. Chem Res Toxicol 29(5):851–859; 10.1021/acs.chemrestox.6b00022 . PMID: 26967026.
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