2016
Patlewicz G , Casati S, Basketter D, Asturiol D, Roberts DW, Lepoittevin J-P, Aschberger K. 2016. Can currently available non-animal methods detect pre and pro haptens relevant for skin sensitization? Regul Toxicol Pharmacol 82(10):147-155;p doi: 10.1016/j.yrtph.2016.08.007 . PMID: 27569201.
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Topics: Adverse outcome pathways (AOPs)
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57(9):706-716; doi: 10.1002/em.22064 . PMID: 27859739.
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Topics: chromium , risk assessment , transcriptomics
Roberts DW, Api AM, Patlewicz G , Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007 . PMID: 27424000.
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Topics: computational toxicology
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 . PMID: 27233922.
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Topics: Air Quality , mode of action , Systematic Review
De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M , Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmaco l 306(Sept 1):113-119; doi: 10.1016/j.taap.2016.07.004 . PMID: 27404458.
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Topics: chromium
Kirman CR, Suh M , Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC, Harris MA, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling. Toxicol Appl Pharmacol 306(Sep 1):120-133; doi: 10.1016/j.taap.2016.07.002 . PMID: 27396814.
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Topics: chromium
Richard A, Judson R, Houck K, Grulke C, Volarath P, Thillainadarajah I, Yang C,…, Patlewicz G , et al. 2016. The ToxCast chemical landscape: Paving the road to 21st century toxicology. Chem Res Toxicol 29(8):1225-1251; doi: 10.1021/acs.chemrestox.6b00135 . PMID: 27367298.
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Topics: computational toxicology
Suh M , Thompson CM , Brorby GP , Mittal L , Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(Aug):74-82; doi: 10.1016/j.yrtph.2016.05.009 . PMID: 27177823.
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Topics: Cancer , cobalt , Metals , risk assessment
Shah I, Liu J, Judson RS, Thomas R, Patlewicz G . 2016. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. Reg Toxicol Pharmacol 79(Aug):12-24; doi: 10.1016/j.yrtph.2016.05.008 . PMID: 27174420.
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Topics: read-across
Samuel GO, Hoffmann S, Wright R, Lalu MM, Patlewicz G , Becker RA, DeGeorge GL, Fergusson D, et al. 2016. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review. Environ Int 92-93(July-Aug):630-646; doi: 10.1016/j.envint.2016.03.010 . PMID: 27039952.
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