2018
Patlewicz G , Wambaugh JF, Felter S, Simon TW, Becker RA. 2018. Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a risk-based prioritization approach for thousands of chemicals. Comput Toxicol 7(Aug):58-67; doi: 10.1016/j.comtox.2018.07.002 . PMID: 31338483.
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Topics: modeling , NAMs
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86 . PMID: 30070899.
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Topics: test methods
Myatt GJ, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A,…, Patlewicz G , et al. 2018. In silico toxicology protocols. Regul Toxicol Pharmacol 96(July):1-17; doi: 10.1016/j.yrtph.2018.04.014 . PMID: 29678766.
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Topics: computational toxicology
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96(Jul):178–189; doi: 10.1016/j.yrtph.2018.05.006 . PMID: 29738809.
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Topics: carcinogens , mode of action , risk assessment
Proctor DM, Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 . PMID: 29684431.
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Topics: Adverse outcome pathways (AOPs) , Cancer , genotoxicity
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
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Topics: chromium , water
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
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Topics: modeling
Klaren WD , Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 . PMID: 28940161.
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Topics: Metals , PCBs
Suh M , Proctor DM, Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 . PMID: 29689363.
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