2018
Wikoff D , Urban JD , Harvey S , Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.
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Topics: risk assessment , Systematic Review , trichloroethylene
Roberts DW, Patlewicz G . 2018. Non-animal assessment of skin sensitization hazard – Is an integrated testing strategy needed, and if so what should be integrated? J Appl Toxicol 38(1):41-50; doi: 10.1002/jat.3479 . PMID: 28543848.
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Topics: Adverse outcome pathways (AOPs) , modeling
Doepker C, Franke K, Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D . 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10(10):1536; doi: 10.3390/nu10101536 .
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Topics: food safety , Food science , Systematic Review
2017
Williams A, Grulke C, Edwards J, McEachran A, Mansouri K, Baker N, Patlewicz G , Shah I, et al. 2017. The CompTox Chemistry Dashboard–A community data resource for environmental chemistry. J Cheminform 9(1):61; doi: 10.1186/s13321-017-0247-6 . PMID: 29185060.
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Topics: computational toxicology
Liu J, Patlewicz G , Williams A, Thomas RS, Shah I. 2017. Predicting organ toxicity using in vitro bioactivity data and chemical structure. Chem Res Toxicol 30(11):2046-2059; doi: 10.1021/acs.chemrestox.7b00084 . PMID: 28768096.
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Topics: computational toxicology , modeling
Pradeep P, Mansouri K, Patlewicz G , Judson RS. 2017. A systematic evaluation of analogs and automated read-across prediction of estrogenicity: A case study using hindered phenols. Comput Toxicol 4(Nov):22-30; doi: 10.1016/j.comtox.2017.09.001 . PMID: 30057968.
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Topics: read-across
Franzen A , Greene T, Van Landingham C, Gentry R. 2017. Toxicology of octamethylcyclotetrasiloxane (D4). Toxicol Lett 279(Suppl 1):2–22. doi: 10.1016/j.toxlet.2017.06.007 . PMID: 28645863.
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Topics: inhalation toxicology , mode of action , pharmacokinetics
Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5)621-640; doi: 10.1002/jat.3412 .
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Topics: pharmacokinetics , Toxicology
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.
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Topics: Toxicology
Thompson CM, Suh M , Proctor DM, Haws LC, Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutation Res 823:45-57.
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