Publications

Helman G, Shah I, Williams AJ, Edwards J, Dunne J, Patlewicz G. 2019. Generalized Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard. ALTEX 36(3):462-465; doi: 10.14573/altex.1811292. PMID: 30741315.

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March 1):112–127; doi: 10.1016/j.cbi.2019.01.025. PMID: 30763550.

Pradeep P, Carlson LM, Judson R, Lehmann GM, Patlewicz G. 2019. Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls. Regul Toxicol Pharmacol 101(Feb):12-23; doi: 10.1016/j.yrtph.2018.10.013. PMID: 30359698.

Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, Ring C, Proctor D. 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol 49(2):140-159; doi: 10.1080/10408444.2019.1578730. PMID: 30896278.

Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335; doi: 10.1093/toxsci/kfy279. PMID: 30423162.

Patlewicz G, Richard AM, Williams AJ, Grulke CM, Sams R, Lambert J, Noyes P, DeVito MJ, et al. 2019. A chemical category-based prioritization approach for selecting 75 per- and polyfluoroalkyl substances (PFAS) for tiered toxicity and toxicokinetic testing. Environ Health Perspect 127(1):14501; doi: 10.1289/EHP4555. PMID: 30632786.

Kleinstreuer NC, Karmaus A, Mansouri K, Allen D, Fitzpatrick J, Patlewicz G. 2018. Predictive models for acute oral systemic toxicity: A workshop to bridge the gap from research to regulation. Comput Toxicol 8(11):21-24; doi: 10.1016/j.comtox.2018.08.002. PMID: 30320239.

Helman G, Shah I, Patlewicz G. 2018. Extending the Generalized Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance. Comput Toxicol 8(Nov):34-50; doi: 10.1016/j.comtox.2018.07.001. PMID: 31667446.

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001. PMID: 30240830.

Nelms MD, Mellow CL, Enoch SJ, Judson RS, Patlewicz G, Richard AM, Madden JM, Cronin MTD, Edwards SW. 2018. A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions. Comput Toxicol 8(Nov):1-12; doi: 10.1016/j.comtox.2018.08.003. PMID: 36779220.