2018
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96(Jul):178–189; doi: 10.1016/j.yrtph.2018.05.006 . PMID: 29738809.
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Topics: carcinogens , mode of action , risk assessment
Proctor DM, Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 . PMID: 29684431.
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Topics: Adverse outcome pathways (AOPs) , Cancer , genotoxicity
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
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Topics: chromium , water
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
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Topics: modeling
Klaren WD , Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 . PMID: 28940161.
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Topics: Metals , PCBs
Suh M , Proctor DM, Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 . PMID: 29689363.
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Topics: carcinogens , chemical safety assessment , consumer products , genotoxicity , microplastics
Patlewicz G , Cronin MTD, Helman G, Lambert JC, Lizarraga LE, Shah I. 2018. Navigating through the minefield of read-across frameworks: A commentary perspective. Comput Toxicol 6(May):39-54; doi: 10.1016/j.comtox.2018.04.002 .
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Topics: computational toxicology , NAMs
Clippinger A, Allen D, Jarabek AM, Corvaro M, Gaça M, Gehen S, Hotchkiss JA, Patlewicz G , et al. 2018. Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report. Toxicol In Vitro 48(April):53-70; doi: 10.1016/j.tiv.2017.12.011 . PMID: 29277654.
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Topics: inhalation toxicology , NAMs , regulatory toxicology
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM, Rager JE, Haws LC, Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545 . PMID: 29064106.
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Topics: chromium , pharmacokinetics
Wikoff D , Urban JD , Harvey S , Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330 . PMID: 29357719.
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