2018
Helman G, Shah I, Patlewicz G . 2018. Extending the Generalized Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance. Comput Toxicol 8(Nov):34-50; doi: 10.1016/j.comtox.2018.07.001 . PMID: 31667446.
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Topics: NAMs
Nelms MD, Mellow CL, Enoch SJ, Judson RS, Patlewicz G , Richard AM, Madden JM, Cronin MTD, Edwards SW. 2018. A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions. Comput Toxicol 8(Nov):1-12; doi: 10.1016/j.comtox.2018.08.003 . PMID: 36779220.
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Topics: Adverse outcome pathways (AOPs) , computational toxicology
Clippinger AJ, Allen D, Behrsing H, BéruBé KA, Bolger MA, Casey W, DeLorme M,…, Patlewicz G , et al. 2018. Pathway-based predictive approaches for non-animal assessment of acute inhalation hazard determination. Toxicol in Vitro 52(Oct):131-145; doi: 10.1016/j.tiv.2018.06.009 . PMID: 29908304.
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Topics: Adverse outcome pathways (AOPs) , risk assessment
Borghoff SJ, Fitch S , Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001 .
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Topics: PFAS
Patlewicz G , Wambaugh JF, Felter S, Simon TW, Becker RA. 2018. Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a risk-based prioritization approach for thousands of chemicals. Comput Toxicol 7(Aug):58-67; doi: 10.1016/j.comtox.2018.07.002 . PMID: 31338483.
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Topics: modeling , NAMs
Myatt GJ, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A,…, Patlewicz G , et al. 2018. In silico toxicology protocols. Regul Toxicol Pharmacol 96(July):1-17; doi: 10.1016/j.yrtph.2018.04.014 . PMID: 29678766.
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