2019
Nelms MD, Lougee R, Roberts DW, Richard A, Patlewicz G . 2019. Comparing and contrasting the coverage of publicly available structural alerts for protein binding. Comput Toxicol 12(Nov):100100; doi: 10.1016/j.comtox.2019.100100 . PMID: 37701288.
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Topics: toxicokinetics
Helman G, Shah I, Patlewicz G . 2019. Transitioning the Generalized Read-Across approach (GenRA) to quantitative predictions: A case study using acute oral toxicity data. Comput Toxicol 12(Nov):1000097; doi: 10.1016/j.comtox.2019.100097 . PMID: 33623834.
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Topics: NAMs
Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C , Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106(Aug):210–223; doi: 10.1016/j.yrtph.2019.04.015 .
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Topics: formaldehyde , risk assessment
Clewell RA, Thompson CM , Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March):112–127; doi: 10.1016/j.cbi.2019.01.025 .
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Topics: carcinogens , risk assessment
van de Ligt J, Borghoff SJ , Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4)1606-1616; doi: 10.1093/tas/txz153 .
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Topics: Food science
Thompson CM , Fitch SE , Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39(9):1267–1282; doi: 10.1002/jat.3812 .
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Topics: benchmark dose estimation (BMD) , PFAS , water
Yoon M, Ring C, Van Landingham CB, Suh M , Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695
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Topics: Toxicology
Webster F, Gagne M, Patlewicz G , Pradeep P, Trefiak N, Judson R, Barton-Maclaren TS. 2019. Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study. Regul Toxicol Pharmacol 106(Aug):278-291; doi: 10.1016/j.yrtph.2019.05.017 . PMID: 31121201.
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Topics: NAMs
Patlewicz G , Lizarraga L, Rua D, Allen DG, Daniel A, Fitzpatrick SC, Garcia-Reyero N, Gordon J, et al. 2019. Exploring current read-across applications and needs among selected US federal agencies. Regul Toxicol Pharmacol 106(Aug):197-209; doi: 10.1016/j.yrtph.2019.05.011 . PMID: 31078681.
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Topics: NAMs
Wikoff D , Haws L Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol , doi: 10.1002/jat.3814, open access.
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