2017
Kirman CR, Proctor D, Suh M , Haws L, Harris M, Thompson C , Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , modeling , pharmacokinetics
Rager JE, Thompson CM , Ring C, Fry RC, Harris MA. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , mode of action , transcriptomics
Martini C, Rashid A, Paleja A, Lea I , Fostel JM. Chemical Effects in Biological Systems (CEBS) database: Treatment-related findings. Abstract 1381-P119. Presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: risk assessment
Iwata Y, Klaren W , Grimm F, Rusyn I. A multidimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
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Topics: chemical safety assessment , Exposure Assessment
2016
Rager J, Thompson C , Auerbach S, Fry R. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, Kansas City, KS, September 2016.
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Topics: arsenic
Gadupudi GS, Klaren WD , Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology, Central States Regional Meeting, Iowa City, IA, 2016. Also presented at NIEHS Obesity Grantee Meeting and 25 Years of Endocrine Disruption Workshop, NIH, Bethesda, MD, 2016.
Topics: PCBs
Klaren WD , Vine D, Vogt S, Robertson LW. Evaluation of the spatial distribution of hepatic metals following PCB126 exposure with x-ray fluorescence microscopy. Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.
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Topics: Metals , microscopy , PCBs
Klaren WD , Iwata Y, Lebakken CS, Grimm FA, Rusyn I. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. College of Veterinary Medicine Graduate Student and Postdoc Research Symposium, Texas A&M University, 2016.
Topics: test methods
Borghoff SJ . Organization and review of mechanistic data according to “Ten Key Characteristics of Carcinogens” (TKCC) {Smith et al., 2016}. Presented at the 42nd Annual Summer Meeting of the Toxicology Forum, Salt Lake City, UT, July 2016.
Topics: carcinogens
DeVito MJ, Borghoff SJ , Zorilla LM, Shockley K, Kissling G, Travlos G. The effects of a high fat (HF) diet on male diversity outbred (DO) mice. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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