2017
Borghoff SJ , Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: modeling , pharmacokinetics
Thompson C , Kirman C, Suh M , Proctor D, Haws L, Harris M, Hays S. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , dose-response , pharmacokinetics
Mease K, Kimzey A , Lansita J. Failed dose formulation analysis during a GLP study — Now what? Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: dose-response , drug development
Suh M, Harvey S, Wikoff D, Mittal L, Ring C, Goodmanson A, Proctor D. Meta-analysis of hexavalent chromium and stomach cancer. Poster presented at Society of Toxicology 56th Annual Meeting, March 13, Baltimore, MD, March 2017.
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Topics: Cancer , chromium , meta-analysis
Doepker D, Tyndall K, Lane R, Wikoff D , Thompson C , Harvey S , Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: food additives , food safety , Food science
Chappell G, Welsh B, Harvey S , Harris M, Wikoff D . Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: carcinogens , risk assessment
Proctor DM, Suh M , Dunsmore D, Verwiel A, Casteel S. Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: cobalt , Metals , nickel
Kirman CR, Proctor D, Suh M , Haws L, Harris M, Thompson C , Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , modeling , pharmacokinetics
Rager JE, Thompson CM , Ring C, Fry RC, Harris MA. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , mode of action , transcriptomics
Martini C, Rashid A, Paleja A, Lea I , Fostel JM. Chemical Effects in Biological Systems (CEBS) database: Treatment-related findings. Abstract 1381-P119. Presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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