2017
Wikoff DS , Welsh BT, Henderson R , Brorby G , Britt J , Myers E, Goldberger J, Lieberman HR, O’Brien C, Doepker C. Application of systematic reviews in the evaluation of caffeine safety: Potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Society of Risk Analysis Annual Meeting, Arlington, VA, December 2017.
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Topics: Systematic Review
Wikoff DS , Rager JE, Harvey S , Haws L, Chappell G, Borghoff S . Development and refinement of a framework for quantitative consideration of study quality and relevance in the evaluation of mechanistic data based on key characteristics of carcinogens. Society of Risk Analysis Annual Meeting, Arlington, VA, December 2017.
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Topics: carcinogens
Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I , Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Poster P035. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017.
Topics: computational toxicology
Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S . 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.
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Topics: carcinogens , Systematic Review
Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at 56th Society of Toxicology Annual Meeting. March 15, Baltimore, MD, March 2017.
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Topics: chromium
Borghoff SJ , Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: modeling , pharmacokinetics
Thompson C , Kirman C, Suh M , Proctor D, Haws L, Harris M, Hays S. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , dose-response , pharmacokinetics
Mease K, Kimzey A , Lansita J. Failed dose formulation analysis during a GLP study — Now what? Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: dose-response , drug development
Suh M, Harvey S, Wikoff D, Mittal L, Ring C, Goodmanson A, Proctor D. Meta-analysis of hexavalent chromium and stomach cancer. Poster presented at Society of Toxicology 56th Annual Meeting, March 13, Baltimore, MD, March 2017.
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Topics: Cancer , chromium , meta-analysis
Doepker D, Tyndall K, Lane R, Wikoff D , Thompson C , Harvey S , Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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