Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118(Dec):104788; doi: 10.1016/j.yrtph.2020.104788 . PMID: 33153971.
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Publication: Manuscripts
/ Topics: carcinogens , modeling
Nelms MD, Karmaus AL, Patlewicz G . 2020. An evaluation of the performance of selected (Q)SARs/expert systems for predicting acute oral toxicity. Comput Toxicol 16(Nov):100135; doi: 10.1016/j.comtox.2020.100135 . PMID: 33163737.
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Publication: Manuscripts
/ Topics: modeling
Thompson CM , Gentry R, Fitch S , Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952; doi: 10.1080/10408444.2020.1854679 . PMID: 33599198.
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Publication: Manuscripts
/ Topics: formaldehyde
Gentry R, Thompson CM , Franzen A , Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918; doi: 10.1080/10408444.2020.1854678 . PMID: 33538218.
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Publication: Manuscripts
/ Topics: Cancer , formaldehyde
Pradeep P, Patlewicz G , Pearce R, Wambaugh J, Wetmore B, Judson R. 2020. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment. Comput Toxicol 16(Nov):100136; doi: 10.1016/j.comtox.2020.100136 . PMID: 34124416.
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Publication: Manuscripts
/ Topics: risk assessment , toxicokinetics
Fryzek J, Suh M , Movva N, Bylsma L. 2020. Protocol: Systematic literature review and meta-analysis of respiratory syncytial virus (RSV) testing patterns, RSV burden, and RSV clinical sequalae among infants and children up to 5 years of age living in the United States. PROSPERO CRD42020162991 .
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Publication: Protocol Registrations
/ Topics: Epidemiology , meta-analysis , Systematic Review
Thompson CM , Donahue DA, Hobbs C, Costecalde Y, Franzen A , Suh M , Proctor DM, Harris MA. 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116(Oct):104729; doi: 10.1016/j.yrtph.2020.104729 . PMID: 32652207.
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Publication: Manuscripts
/ Topics: chromium , Environmental Science , Metals
Suh M , Jiang X, Movva N, Fryzek J, Bylsma L, Rizzo C, Nelson CB. Hospitalizations and emergency department visits for respiratory syncytial virus among infants aged <1 year in the United States: An analysis of nationwide inpatient and emergency room data. Presentation to IDWeek Virtual Conference on Infectious Disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Nelms MD, Patlewicz G . 2020. Derivation of new threshold of toxicological concern values for exposure via inhalation for environmentally-relevant chemicals. Front Toxicol 2:580347; doi: 10.3389/ftox.2020.580347 . PMID: 35296122.
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Publication: Manuscripts
/ Topics: inhalation toxicology
Rankin DA, Haddadin Z, Lipworth L, Fryzek J, Suh M , Shepard DS, McHenry R, Varjabedian R, et al. Comparison of clinical presentations and burden of respiratory syncytial virus in infants across three distinct healthcare settings. IDWeek Virtual Conference on Infectious Disease, October 2020.
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