Publication Topic

Rovida C, Escher SE, Herzler M, Bennekou SH, Kamp H, Kroese DE, Maslankiewicz L, Moné MJ, Patlewicz G, et al. 2021. NAM-supported read-across: From case studies to regulatory guidance in safety assessment. ALTEX 38(1):140-150; doi: 10.14573/altex.2010062. PMID: 33452529.

House JS, Grimm FA, Klaren WD, Dalzell A, Kuchi S, Zhang S, Lenz K, Boogaard PJ, Ketelsegers HB, Gant TW, Wright FA, Rusyn I. 2020. Grouping of UVCB substances with new approach methodologies (NAMs) data. ALTEX 38(1):123–137; doi: 10.14573/altex.2006262.

Rovida C, Barton-Maclaren T, Benfenati E, Caloni F, Chandrasekera PC, Chesne C, Cronin MTD,.., Patlewicz G, et al. 2020. Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology. ALTEX 37(4):579-606; doi: 10.14573/altex.1912181. PMID: 32369604.

Nelms MD, Pradeep P, Patlewicz G. 2019. Evaluating potential refinements to existing Threshold of Toxicological Concern (TTC) values for environmentally-relevant compounds. Regul Toxicol Pharmacol 109(Dec):104505; doi: 10.1016/j.yrtph.2019.104505. PMID: 31639428.

Helman G, Shah I, Patlewicz G. 2019. Transitioning the Generalized Read-Across approach (GenRA) to quantitative predictions: A case study using acute oral toxicity data. Comput Toxicol 12(Nov):1000097; doi: 10.1016/j.comtox.2019.100097. PMID: 33623834.

Webster F, Gagne M, Patlewicz G, Pradeep P, Trefiak N, Judson R, Barton-Maclaren TS. 2019. Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study. Regul Toxicol Pharmacol 106(Aug):278-291; doi: 10.1016/j.yrtph.2019.05.017. PMID: 31121201.

Patlewicz G, Lizarraga L, Rua D, Allen DG, Daniel A, Fitzpatrick SC, Garcia-Reyero N, Gordon J, et al. 2019. Exploring current read-across applications and needs among selected US federal agencies. Regul Toxicol Pharmacol 106(Aug):197-209; doi: 10.1016/j.yrtph.2019.05.011. PMID: 31078681.

Helman G, Shah I, Williams AJ, Edwards J, Dunne J, Patlewicz G. 2019. Generalized Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard. ALTEX 36(3):462-465; doi: 10.14573/altex.1811292. PMID: 30741315.

Helman G, Shah I, Patlewicz G. 2018. Extending the Generalized Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance. Comput Toxicol 8(Nov):34-50; doi: 10.1016/j.comtox.2018.07.001. PMID: 31667446.

Patlewicz G, Wambaugh JF, Felter S, Simon TW, Becker RA. 2018. Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a risk-based prioritization approach for thousands of chemicals. Comput Toxicol 7(Aug):58-67; doi: 10.1016/j.comtox.2018.07.002. PMID: 31338483.